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Peer-reviewedCC BYCureus

Subependymal Giant Cell Astrocytoma Mimicking Recurrent Ependymoma: Imaging Clues to the Diagnosis of Tuberous Sclerosis Complex

  1. 1Diagnostic and Interventional Radiology, Mohammed VI University Hospital, Tangier, MAR

Abstract

Tuberous sclerosis complex (TSC), also known as Bourneville disease, is a multisystem genetic disorder that can involve the central nervous system. We report the case of an adolescent with a history of intraventricular ependymoma resection during childhood and ventriculoperitoneal shunt placement who presented with symptoms of intracranial hypertension. Brain imaging revealed a right intraventricular solid-cystic mass involving the foramen of Monro, associated with subependymal nodules and cortical tubers, suggesting previously undiagnosed TSC. This case emphasizes the importance of recognizing imaging features of TSC in patients presenting with intraventricular tumors to ensure accurate diagnosis and appropriate management.

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BibTeX
@article{bouymajjan2026subependymal,
  title = {{Subependymal Giant Cell Astrocytoma Mimicking Recurrent Ependymoma: Imaging Clues to the Diagnosis of Tuberous Sclerosis Complex}},
  author = {Abdelilah Bouymajjan and Asmae Oulad Amar and El Mahdi Choukri and Ali Meqor and Siham Alaoui Rachidi},
  journal = {Cureus},
  year = {2026},
  month = sep,
  doi = {10.7759/cureus.117140},
  url = {https://europepmc.org/article/PMC/PMC13718258},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Subependymal Giant Cell Astrocytoma Mimicking Recurrent Ependymoma: Imaging Clues to the Diagnosis of Tuberous Sclerosis Complex
AU  - Abdelilah Bouymajjan
AU  - Asmae Oulad Amar
AU  - El Mahdi Choukri
AU  - Ali Meqor
AU  - Siham Alaoui Rachidi
PY  - 2026
DA  - 2026/09/29
JO  - Cureus
DO  - 10.7759/cureus.117140
UR  - https://europepmc.org/article/PMC/PMC13718258
AB  - Tuberous sclerosis complex (TSC), also known as Bourneville disease, is a multisystem genetic disorder that can involve the central nervous system. We report the case of an adolescent with a history of intraventricular ependymoma resection during childhood and ventriculoperitoneal shunt placement who presented with symptoms of intracranial hypertension. Brain imaging revealed a right intraventricular solid-cystic mass involving the foramen of Monro, associated with subependymal nodules and cortical tubers, suggesting previously undiagnosed TSC. This case emphasizes the importance of recognizing imaging features of TSC in patients presenting with intraventricular tumors to ensure accurate diagnosis and appropriate management.
SN  - 2168-8184
ER  -