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Peer-reviewedCC BY-NC-NDClinical case reports

Diffuse Leptomeningeal Glioneuronal Tumor With Initial Diagnosis of Pilocytic Astrocytoma With Anaplasia: A Case Study

  1. 1University of Nebraska Medical Center
  2. 2Emory University School of Medicine
  3. 3Mayo Clinic Arizona

Abstract

Diffuse leptomeningeal glioneuronal tumor is a rare central nervous system tumor with imaging findings including leptomeningeal enhancement and nodular/cystic lesions. This case highlights how patients can have differing imaging features, requiring whole‐genome DNA methylation profiling for diagnosis, and demonstrates successful treatment after initial descriptive diagnosis of pilocytic astrocytoma with anaplasia.

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BibTeX
@article{zhou2026diffuse,
  title = {{Diffuse Leptomeningeal Glioneuronal Tumor With Initial Diagnosis of Pilocytic Astrocytoma With Anaplasia: A Case Study}},
  author = {Anita Zhou and Joseph Carmicheal and Jie Chen and Chi Zhang},
  journal = {Clinical case reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73701},
  url = {https://europepmc.org/article/PMC/PMC13675905},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Diffuse Leptomeningeal Glioneuronal Tumor With Initial Diagnosis of Pilocytic Astrocytoma With Anaplasia: A Case Study
AU  - Anita Zhou
AU  - Joseph Carmicheal
AU  - Jie Chen
AU  - Chi Zhang
PY  - 2026
DA  - 2026/10/01
JO  - Clinical case reports
DO  - 10.1002/ccr3.73701
UR  - https://europepmc.org/article/PMC/PMC13675905
AB  - Diffuse leptomeningeal glioneuronal tumor is a rare central nervous system tumor with imaging findings including leptomeningeal enhancement and nodular/cystic lesions. This case highlights how patients can have differing imaging features, requiring whole‐genome DNA methylation profiling for diagnosis, and demonstrates successful treatment after initial descriptive diagnosis of pilocytic astrocytoma with anaplasia.
SN  - 2050-0904
ER  -