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Peer-reviewedCC BYEngMedicine

Silk biomaterials for precision medicine: From silk science to medical engineering

  1. 1Department of Orthopedics, Nantong First People's Hospital, School of Medicine, Southeast University, Nantong, 226000, China
  2. 2Department of Orthopedics, Nantong First People's Hospital, School of Medicine, Southeast University, Nantong, 226000, China; Jiangsu Key Laboratory for Biomaterials and Devices, Southeast University, Nanjing, 210096, China; Corresponding author. Department of Orthopedics, Nantong First People's Hospital, School of Medicine, Southeast University, 226000, Nantong, China.

Abstract

Silk biomaterials, particularly Bombyx mori silk fibroin (SF) biomaterials, have emerged as a versatile platform for biomedical applications owing to their inherent biocompatibility, tunable hierarchical structure, excellent processability, and facile functionalization. Recent advances in silk science and medical engineering have enabled precise medical monitoring and intervention using SF biomaterials by integrating the molecular design, structural organization, and processing strategies. Herein, we provide an overview of these advances and discuss the applications of SF biomaterials in tissue engineering, drug delivery, and bioelectronic devices, highlighting the potential for structural and functional design and fabrication based on SF building blocks.

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BibTeX
@article{lu2026silk,
  title = {{Silk biomaterials for precision medicine: From silk science to medical engineering}},
  author = {Zhiyuan Lu and Renwang Sheng and Wei Zhang},
  journal = {EngMedicine},
  year = {2026},
  month = oct,
  doi = {10.1016/j.engmed.2026.100162},
  url = {https://doi.org/10.1016/j.engmed.2026.100162},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Silk biomaterials for precision medicine: From silk science to medical engineering
AU  - Zhiyuan Lu
AU  - Renwang Sheng
AU  - Wei Zhang
PY  - 2026
DA  - 2026/10/30
JO  - EngMedicine
DO  - 10.1016/j.engmed.2026.100162
UR  - https://doi.org/10.1016/j.engmed.2026.100162
AB  - Silk biomaterials, particularly Bombyx mori silk fibroin (SF) biomaterials, have emerged as a versatile platform for biomedical applications owing to their inherent biocompatibility, tunable hierarchical structure, excellent processability, and facile functionalization. Recent advances in silk science and medical engineering have enabled precise medical monitoring and intervention using SF biomaterials by integrating the molecular design, structural organization, and processing strategies. Herein, we provide an overview of these advances and discuss the applications of SF biomaterials in tissue engineering, drug delivery, and bioelectronic devices, highlighting the potential for structural and functional design and fabrication based on SF building blocks.
SN  - 2950-4899
ER  -