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Peer-reviewedCC BY-NC-ND 4.0JACC Case Reports

Psychosocial Stress–Induced Takotsubo Syndrome in a Male Patient

  1. 1Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA

Abstract

Background: Takotsubo syndrome (TTS) predominantly affects postmenopausal women after emotional or physical stress; men account for only ∼10% of cases and are usually triggered by physical precipitants.

Case Summary: A 48-year-old man presented with 24 hours of dyspnea following psychosocial stress related to financial and occupational strain. He was diagnosed with TTS complicated by dynamic left ventricular outflow tract obstruction and 4 discrete apical thrombi identified on cardiac magnetic resonance, and recovered fully with β-blockade and anticoagulation.

Discussion: This case is doubly atypical in sex and trigger. Severe complications arose despite a lower-risk trigger profile, and cardiac magnetic resonance was essential to detect thrombi and exclude infarction and myocarditis.

Take-Home Message: Male patients with psychosocial stress–triggered TTS are rare but face significant risk of severe complications, and multimodality imaging including cardiac magnetic resonance is helpful in this underrecognized population.

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BibTeX
@article{beesley2026psychosocial,
  title = {{Psychosocial Stress–Induced Takotsubo Syndrome in a Male Patient}},
  author = {Hassan Beesley and Minel Soroa and Stamatios Lerakis and Deepak L. Bhatt and Solomon W. Bienstock},
  journal = {JACC Case Reports},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jaccas.2026.110015},
  url = {https://doi.org/10.1016/j.jaccas.2026.110015},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Psychosocial Stress–Induced Takotsubo Syndrome in a Male Patient
AU  - Hassan Beesley
AU  - Minel Soroa
AU  - Stamatios Lerakis
AU  - Deepak L. Bhatt
AU  - Solomon W. Bienstock
PY  - 2026
DA  - 2026/09/03
JO  - JACC Case Reports
DO  - 10.1016/j.jaccas.2026.110015
UR  - https://doi.org/10.1016/j.jaccas.2026.110015
AB  - Background: Takotsubo syndrome (TTS) predominantly affects postmenopausal women after emotional or physical stress; men account for only ∼10% of cases and are usually triggered by physical precipitants.  Case Summary: A 48-year-old man presented with 24 hours of dyspnea following psychosocial stress related to financial and occupational strain. He was diagnosed with TTS complicated by dynamic left ventricular outflow tract obstruction and 4 discrete apical thrombi identified on cardiac magnetic resonance, and recovered fully with β-blockade and anticoagulation.  Discussion: This case is doubly atypical in sex and trigger. Severe complications arose despite a lower-risk trigger profile, and cardiac magnetic resonance was essential to detect thrombi and exclude infarction and myocarditis.  Take-Home Message: Male patients with psychosocial stress–triggered TTS are rare but face significant risk of severe complications, and multimodality imaging including cardiac magnetic resonance is helpful in this underrecognized population.
SN  - 2666-0849
ER  -