Beyond breathing: Lung as a sensory organ
Abstract
The lung, one the largest branching organs in our body and vital for survival at first breath, is commonly known as the gas exchange organ. Recent novel findings on lung sensing cells, molecules, and lung–brain crosstalk in the emerging discipline of interoception have highlighted the consideration of the lung as a sensory organ. Acknowledging the central importance of lung sensing to human health and disease, the National Heart, Lung, and Blood Institute convened a workshop to synthesize the past, current, and future of lung sensing research, with in-person presentations by approximately 20 interdisciplinary experts and a large virtual audience. Here, we highlight the key topics discussed and summarize a blueprint for the future in this important field.
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BibTeX
@article{jendzjowsky2026beyond,
title = {{Beyond breathing: Lung as a sensory organ}},
author = {Nicholas Jendzjowsky and Christin S Kuo and Leah R Reznikov and Zhijian Chen and Peng Li and Sara Prescott and Yin Liu and Laura Seeholzer and Daniel J Tschumperlin and Thomas E Taylor-Clark and Jay Rajagopal and Adam L Haber and Alexandra Noël and Maya Kotas and Matthew G Drake and Christina Pabelick and Jody Rosenblatt and Gary Mouradian and Yujuan Su and Christian Gomez and Qing Lin and Qing Lu and Emmanuel F Mongodin and Louis Vuga and Guofei Zhou and Y S Prakash and Xin Sun},
journal = {American Journal of Respiratory Cell and Molecular Biology},
year = {2026},
month = jun,
doi = {10.1093/ajrcmb/aanag111},
url = {https://doi.org/10.1093/ajrcmb/aanag111},
note = {CC BY-NC 4.0},
}
RIS
TY - JOUR
TI - Beyond breathing: Lung as a sensory organ
AU - Nicholas Jendzjowsky
AU - Christin S Kuo
AU - Leah R Reznikov
AU - Zhijian Chen
AU - Peng Li
AU - Sara Prescott
AU - Yin Liu
AU - Laura Seeholzer
AU - Daniel J Tschumperlin
AU - Thomas E Taylor-Clark
AU - Jay Rajagopal
AU - Adam L Haber
AU - Alexandra Noël
AU - Maya Kotas
AU - Matthew G Drake
AU - Christina Pabelick
AU - Jody Rosenblatt
AU - Gary Mouradian
AU - Yujuan Su
AU - Christian Gomez
AU - Qing Lin
AU - Qing Lu
AU - Emmanuel F Mongodin
AU - Louis Vuga
AU - Guofei Zhou
AU - Y S Prakash
AU - Xin Sun
PY - 2026
DA - 2026/06/09
JO - American Journal of Respiratory Cell and Molecular Biology
DO - 10.1093/ajrcmb/aanag111
UR - https://doi.org/10.1093/ajrcmb/aanag111
AB - The lung, one the largest branching organs in our body and vital for survival at first breath, is commonly known as the gas exchange organ. Recent novel findings on lung sensing cells, molecules, and lung–brain crosstalk in the emerging discipline of interoception have highlighted the consideration of the lung as a sensory organ. Acknowledging the central importance of lung sensing to human health and disease, the National Heart, Lung, and Blood Institute convened a workshop to synthesize the past, current, and future of lung sensing research, with in-person presentations by approximately 20 interdisciplinary experts and a large virtual audience. Here, we highlight the key topics discussed and summarize a blueprint for the future in this important field.
SN - 1044-1549
SN - 1535-4989
ER -