Skip to content
DraconiticResearch
Search Sources API
206,690 studies31 sourcesUpdated just now
Peer-reviewedCC BY-NC-ND 4.0JACC Case Reports

Radiation Dose Optimization in Coronary CT Angiography

  • Muhammad Kashif1
  • Danish Waris Ali2
  • Adeel Ur Rahman Siddiqui2,3
  • Muhammad Ali2
  • Sumair Ahmed2
  • Muhammad Arshad1
  • Bashir Hanif1,2
  1. 1Department of Clinical Research Cardiology, Tabba Heart Institute, Karachi, Pakistan
  2. 2Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan
  3. 3Consultant Cardiologist and Director Radiology Tabba Heart Institute, Karachi, Pakistan
Read full textDOICite

Abstract

Background: Coronary computed tomography angiography (CCTA) is increasingly used for the evaluation of coronary artery disease; however, radiation exposure remains a patient safety concern. Data on radiation dose optimization from low- and middle-income countries are limited.

Project Rationale: Tabba Heart Institute Karachi identified opportunities to reduce CCTA radiation exposure through implementation of heart rate and body mass index–guided acquisition protocols while maintaining image quality.

Project Summary: A quality improvement initiative was implemented using patient-specific scanning protocols. A total of 422 CCTA examinations were evaluated, including 117 preintervention and 305 postintervention studies. Median effective radiation dose decreased by 45.5%, from 8.8 mSv to 4.8 mSv (P < 0.001). CCTA dose-length product decreased by 46.5% and total dose-length product by 39.8% (both P < 0.001). No significant differences were observed in image quality metrics or repeat scan rates.

Take-Home Message: Technologist-driven protocol optimization can substantially reduce CCTA radiation exposure without compromising image quality and may serve as a scalable model for cardiovascular imaging programs in resource-constrained settings.

Related

  1. Radiation Dose Reduction in Coronary Computed Tomography Angiography
    Esosa Odigie-Okon, Olushola Ogunleye, Ritika Saxena +6
    JACC Case ReportsPeer-reviewedCC BY-NC-ND 4.0Full textMedical imaging & radiologyPMC
  2. Image quality and radiation dose optimization in CT pulmonary angiography using 120, 100, and 80 kV protocols for pulmonary thromboembolism diagnosis.
    Zubir Shazli, Hanani Abdul Manan, Syeda Humayra +6
    Quantitative imaging in medicine and surgeryPeer-reviewedCC BY-NC-NDFull textMedical imaging & radiologyEurope PMC
  3. Nonlinear and Vessel-Specific Association Between Coronary Artery Calcium Burden and Coronary Computed Tomography Angiography Underestimation of Coronary Stenosis
    Xuzhe Wang, Chengzhuo Wang, Yu Xie +2
    Reviews in cardiovascular medicinePeer-reviewedCC BYFull textCardiovascular medicineEurope PMC
  4. From coronary computed tomography angiography to the cath lab: computed tomography-guided percutaneous coronary intervention of a high-risk left anterior descending artery lesion
    Natalia Krajewska, Łukasz Kołtowski
    Postepy w kardiologii interwencyjnej = Advances in interventional cardiologyPeer-reviewedCC BY-NC-SAFull textSurgery & anaesthesiaEurope PMCPMC
  5. Inflammatory biomarkers show sex-specific associations with cardiometabolic disease and coronary atherosclerosis as assessed by coronary CT angiography
    Daniel O. Bittner, Caroline Roesner, Dorette Raaz-Schrauder +5
    American journal of preventive cardiologyPeer-reviewedCC BYFull textGeneral medicineEurope PMC

Cite

BibTeXRIS
BibTeX
@article{kashif2026radiation,
  title = {{Radiation Dose Optimization in Coronary CT Angiography}},
  author = {Muhammad Kashif and Danish Waris Ali and Adeel Ur Rahman Siddiqui and Muhammad Ali and Sumair Ahmed and Muhammad Arshad and Bashir Hanif},
  journal = {JACC Case Reports},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jaccas.2026.109329},
  url = {https://doi.org/10.1016/j.jaccas.2026.109329},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Radiation Dose Optimization in Coronary CT Angiography
AU  - Muhammad Kashif
AU  - Danish Waris Ali
AU  - Adeel Ur Rahman Siddiqui
AU  - Muhammad Ali
AU  - Sumair Ahmed
AU  - Muhammad Arshad
AU  - Bashir Hanif
PY  - 2026
DA  - 2026/09/16
JO  - JACC Case Reports
DO  - 10.1016/j.jaccas.2026.109329
UR  - https://doi.org/10.1016/j.jaccas.2026.109329
AB  - Background: Coronary computed tomography angiography (CCTA) is increasingly used for the evaluation of coronary artery disease; however, radiation exposure remains a patient safety concern. Data on radiation dose optimization from low- and middle-income countries are limited.  Project Rationale: Tabba Heart Institute Karachi identified opportunities to reduce CCTA radiation exposure through implementation of heart rate and body mass index–guided acquisition protocols while maintaining image quality.  Project Summary: A quality improvement initiative was implemented using patient-specific scanning protocols. A total of 422 CCTA examinations were evaluated, including 117 preintervention and 305 postintervention studies. Median effective radiation dose decreased by 45.5%, from 8.8 mSv to 4.8 mSv (P < 0.001). CCTA dose-length product decreased by 46.5% and total dose-length product by 39.8% (both P < 0.001). No significant differences were observed in image quality metrics or repeat scan rates.  Take-Home Message: Technologist-driven protocol optimization can substantially reduce CCTA radiation exposure without compromising image quality and may serve as a scalable model for cardiovascular imaging programs in resource-constrained settings.
SN  - 2666-0849
ER  -