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Peer-reviewedCC BY 4.0PLOS One

Colorectal Lesion diagnosis using transformer and deep learning with multiscale feature interface

  1. 1Department of Computer Engineering & Applications, G.L.A. University, Mathura, Uttar Pradesh, India
  2. 2Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, India
  3. 3Department of Electronics and Communication Engineering, Kuwait College of Science and Technology (KCST), Kuwait City, Kuwait

Abstract

Colorectal cancer is the third most common malignancy worldwide. Manual screening requires expertise and resources. However, advancements in AI (artificial intelligence) have reduced the computation burden and time. Machine and deep learning have recently been used to diagnose colorectal lesions. The requirement of handcrafted features makes machine learning models expertise-dependent. At the same time, classical CNN (convolutional neural network) miss the global attention of the features. This work presents CDCTNet (colorectal diagnosis convolution transformer network), a hierarchical model for colorectal disease detection. Our model utilized two convolution blocks for the local high-dimensional spatial features from the lesion. In addition, the ViT encoder is used in parallel with the CNN block to provide a global correlation of the feature map. Furthermore, we designed an IEM block for the interaction of the features between the convolution block and ViT encoder to improve the attention on the features. The CDCTNet is evaluated on Kather and Kvasir datasets and obtained a precision and Kappa score of 96.60% and 95.02%, respectively. At the same time, CDCTNet has recall and F1 scores of 98.08% and 97.94%.

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BibTeX
@article{yadav2026colorectal,
  title = {{Colorectal Lesion diagnosis using transformer and deep learning with multiscale feature interface}},
  author = {Dhirendra Prasad Yadav and Bhisham Sharma and Julian L. Webber and Abolfazl Mehbodniya},
  journal = {PLOS One},
  year = {2026},
  month = sep,
  doi = {10.1371/journal.pone.0357664},
  url = {https://doi.org/10.1371/journal.pone.0357664},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Colorectal Lesion diagnosis using transformer and deep learning with multiscale feature interface
AU  - Dhirendra Prasad Yadav
AU  - Bhisham Sharma
AU  - Julian L. Webber
AU  - Abolfazl Mehbodniya
PY  - 2026
DA  - 2026/09/03
JO  - PLOS One
DO  - 10.1371/journal.pone.0357664
UR  - https://doi.org/10.1371/journal.pone.0357664
AB  - Colorectal cancer is the third most common malignancy worldwide. Manual screening requires expertise and resources. However, advancements in AI (artificial intelligence) have reduced the computation burden and time. Machine and deep learning have recently been used to diagnose colorectal lesions. The requirement of handcrafted features makes machine learning models expertise-dependent. At the same time, classical CNN (convolutional neural network) miss the global attention of the features. This work presents CDCTNet (colorectal diagnosis convolution transformer network), a hierarchical model for colorectal disease detection. Our model utilized two convolution blocks for the local high-dimensional spatial features from the lesion. In addition, the ViT encoder is used in parallel with the CNN block to provide a global correlation of the feature map. Furthermore, we designed an IEM block for the interaction of the features between the convolution block and ViT encoder to improve the attention on the features. The CDCTNet is evaluated on Kather and Kvasir datasets and obtained a precision and Kappa score of 96.60% and 95.02%, respectively. At the same time, CDCTNet has recall and F1 scores of 98.08% and 97.94%.
SN  - 1932-6203
ER  -