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Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer

1184 VGX-3100 DNA immunotherapy for HPV-16/18–associated cervical high-grade squamous intraepithelial lesions: a phase III randomized trial

  • Ling Li1
  • Jing Li2
  • Wei Wang3
  • Huan Wang4
  • Qi Wang5
  • Shu Li6
  • Yi Zhang7
  • Yi Huang8
  • Jeffrey Skolnik9
  • Chun Fu10
  • Jian Zhao11
  • Shuo Chen12
25 more authors
  • Xiaomei Ma13
  • Yue He14
  • Jiandong Wang15
  • Lingying Wu16
  • Xiujie Sheng17
  • Huafeng Shou18
  • Long Sui19
  • Xiaomao Li20
  • Qionghua Chen21
  • Yanlong Wang22
  • Renfeng Zhao23
  • Qing Cong24
  • Bingzhong Zhang25
  • Nan Yu26
  • Hong Ji27
  • Nenan Lyu28
  • Shuxia Han29
  • Yangqing Ge30
  • Chunfang Ha29
  • Jieqing Zhang31
  • Jusheng An28
  • Jianjun Zhai32
  • Youjin Han33
  • Michael Sumner34
  • David B Weiner35
35 affiliations
  1. 1Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
  2. 2Guangdong Women and Children Hospital, Guangzhou, Guangdong, China
  3. 3University of Toronto, Toronto, Ontario, Canada
  4. 4Nossal Institute for Global Health, The University of Melbourne, Melbourne, Victoria, Australia
  5. 56 School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
  6. 6Department of Rheumatology and Immunology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
  7. 7Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
  8. 8Internal Medicine, The University of Iowa, Iowa City, Iowa, USA
  9. 91Inovio, Plymouth Meeting, PA, USA
  10. 101 Department of Obstetrics and Gynecology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
  11. 11National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, People`s Republic of China
  12. 12Pharmacy Administration and Clinical Pharmacy, Peking University Health Science Centre, Beijing, China
  13. 131 Department of Chronic Disease Epidemiology, Yale University School of Public Health and Yale Cancer Center, New Haven, Connecticut, USA
  14. 142Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA
  15. 152Department of Pathology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China
  16. 164National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Gynecologic Oncology, National Cancer Center/national Clinical Research Center For Cancer/cancer Hospital, Beijing, China
  17. 17Department of Obstetrics and Gynecology, The Third Affiliated Hospital and Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou Medical University, Guangzhou; and
  18. 18Zhejiang Provincial People’s Hospital, Hangzhou, China
  19. 193 Chinese Society for Colposcopy and Cervical Pathology of China Healthy Birth Science Association (CSCCP), Beijing, China
  20. 20Department of Gynecology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China
  21. 216 Department of Gynecology, The First Affiliated Hospital of Xiamen University, Xiamen, China
  22. 22Xiamen Maternal and Child Health Hospital, Xiamen, China
  23. 23Department of Gynecology and Obstetrics, Guangxi Academy of Medical Sciences, The People`s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi Zhuang Autonomous Region, China
  24. 242 Chinese Society for Colposcopy and Cervical Pathology of China Healthy Birth Science Association(CSCCP), Beijing, China
  25. 2510Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
  26. 26Chinese Society for Colposcopy and Cervical Pathology of China Healthy Birth Science Association (CSCCP), Beijing, China
  27. 27Department of Nursing, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China
  28. 28National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  29. 29The General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China
  30. 30Yueyang People’s Hospital, Yueyang, Hunan, China
  31. 31Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China
  32. 32Beijing Tongren Hospital Affiliated to Capital Medical University, Beijing, China
  33. 33Beijing Apollo Saturn Biological Technology Limited, Beijing, China
  34. 34Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA
  35. 35The Wistar Institute, Philadelphia, PA, USA
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Cite

BibTeXRIS
BibTeX
@article{li20261184,
  title = {{1184 VGX-3100 DNA immunotherapy for HPV-16/18–associated cervical high-grade squamous intraepithelial lesions: a phase III randomized trial}},
  author = {Ling Li and Jing Li and Wei Wang and Huan Wang and Qi Wang and Shu Li and Yi Zhang and Yi Huang and Jeffrey Skolnik and Chun Fu and Jian Zhao and Shuo Chen and Xiaomei Ma and Yue He and Jiandong Wang and Lingying Wu and Xiujie Sheng and Huafeng Shou and Long Sui and Xiaomao Li and Qionghua Chen and Yanlong Wang and Renfeng Zhao and Qing Cong and Bingzhong Zhang and Nan Yu and Hong Ji and Nenan Lyu and Shuxia Han and Yangqing Ge and Chunfang Ha and Jieqing Zhang and Jusheng An and Jianjun Zhai and Youjin Han and Michael Sumner and David B Weiner},
  journal = {Journal for ImmunoTherapy of Cancer},
  year = {2026},
  month = nov,
  doi = {10.1136/jitc-2026-sitc2026.1184},
  url = {https://doi.org/10.1136/jitc-2026-sitc2026.1184},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - 1184 VGX-3100 DNA immunotherapy for HPV-16/18–associated cervical high-grade squamous intraepithelial lesions: a phase III randomized trial
AU  - Ling Li
AU  - Jing Li
AU  - Wei Wang
AU  - Huan Wang
AU  - Qi Wang
AU  - Shu Li
AU  - Yi Zhang
AU  - Yi Huang
AU  - Jeffrey Skolnik
AU  - Chun Fu
AU  - Jian Zhao
AU  - Shuo Chen
AU  - Xiaomei Ma
AU  - Yue He
AU  - Jiandong Wang
AU  - Lingying Wu
AU  - Xiujie Sheng
AU  - Huafeng Shou
AU  - Long Sui
AU  - Xiaomao Li
AU  - Qionghua Chen
AU  - Yanlong Wang
AU  - Renfeng Zhao
AU  - Qing Cong
AU  - Bingzhong Zhang
AU  - Nan Yu
AU  - Hong Ji
AU  - Nenan Lyu
AU  - Shuxia Han
AU  - Yangqing Ge
AU  - Chunfang Ha
AU  - Jieqing Zhang
AU  - Jusheng An
AU  - Jianjun Zhai
AU  - Youjin Han
AU  - Michael Sumner
AU  - David B Weiner
PY  - 2026
DA  - 2026/11/08
JO  - Journal for ImmunoTherapy of Cancer
DO  - 10.1136/jitc-2026-sitc2026.1184
UR  - https://doi.org/10.1136/jitc-2026-sitc2026.1184
SN  - 2051-1426
ER  -