Epidemiology of Sudan ebolavirus disease cases in Uganda, January-April, 2025

@article{mfitundinda2026epidemiology,
  title = {{Epidemiology of Sudan ebolavirus disease cases in Uganda, January-April, 2025}},
  author = {Emmanuel Mfitundinda and Daniel Wenani and Hannington Katumba and Gertrude Abbo and Janet Lubega Kobusinge and Charity Mutesi and Patrick Kwizera and Emmanuel Okiror Okello and Annet Mary Namusisi and Joanita Nalwanga and Bridget Ainembabazi and Olive Loryndah Namakula and Joyce Owens Kobusingye and Vianney John Kigongo and Deborah Aujo and Denise Kyomugisha Aman and Martha Dorcas Nalweyiso and Pauline Achom and Nasif Matovu and Michael Mutegeki and Winfred Nakaweesi and Sharon Namasambi and Maria Nakabuye and Justine Wobusobozi and Amina Namwabira and Anne Loy Alupo and Esther Nabatta and Winnie Agwang and Samuel Lugwana and Tracy Rutogire and Ritah Namusoosa and Wilfred Opeli and Robert Namisi Masaba and Martha Nakaye and Florence Nambaziira and Caroline Musubika and Vivian Nakaweesa and Samuel Gidudu and Rebecca Akunzirwe and Jane Frances Zalwango and Mackline Ninsiima and Daniel Eurien and Aggrey Byaruhanga and Sunday Kithula Haggai and Bernard Lubwama and Godfrey Bwire and Moses Ebong and Dansan Atim and Patricia Eyu and Hildah Tendo Nansikombi and Irene Byakatonda Kyamwine and Job Morukileng and Richard Migisha and Benon Kwesiga and Paul Edward Okello and Lilian Bulage and Kami L. Smith and Joseph Ojwang and Sam Wasike and Stephen Balinandi},
  journal = {International Journal of Infectious Diseases},
  year = {2026},
  month = oct,
  doi = {10.1016/j.ijid.2026.109075},
  url = {https://doi.org/10.1016/j.ijid.2026.109075},
  note = {CC BY},
}

TY  - JOUR
TI  - Epidemiology of Sudan ebolavirus disease cases in Uganda, January-April, 2025
AU  - Emmanuel Mfitundinda
AU  - Daniel Wenani
AU  - Hannington Katumba
AU  - Gertrude Abbo
AU  - Janet Lubega Kobusinge
AU  - Charity Mutesi
AU  - Patrick Kwizera
AU  - Emmanuel Okiror Okello
AU  - Annet Mary Namusisi
AU  - Joanita Nalwanga
AU  - Bridget Ainembabazi
AU  - Olive Loryndah Namakula
AU  - Joyce Owens Kobusingye
AU  - Vianney John Kigongo
AU  - Deborah Aujo
AU  - Denise Kyomugisha Aman
AU  - Martha Dorcas Nalweyiso
AU  - Pauline Achom
AU  - Nasif Matovu
AU  - Michael Mutegeki
AU  - Winfred Nakaweesi
AU  - Sharon Namasambi
AU  - Maria Nakabuye
AU  - Justine Wobusobozi
AU  - Amina Namwabira
AU  - Anne Loy Alupo
AU  - Esther Nabatta
AU  - Winnie Agwang
AU  - Samuel Lugwana
AU  - Tracy Rutogire
AU  - Ritah Namusoosa
AU  - Wilfred Opeli
AU  - Robert Namisi Masaba
AU  - Martha Nakaye
AU  - Florence Nambaziira
AU  - Caroline Musubika
AU  - Vivian Nakaweesa
AU  - Samuel Gidudu
AU  - Rebecca Akunzirwe
AU  - Jane Frances Zalwango
AU  - Mackline Ninsiima
AU  - Daniel Eurien
AU  - Aggrey Byaruhanga
AU  - Sunday Kithula Haggai
AU  - Bernard Lubwama
AU  - Godfrey Bwire
AU  - Moses Ebong
AU  - Dansan Atim
AU  - Patricia Eyu
AU  - Hildah Tendo Nansikombi
AU  - Irene Byakatonda Kyamwine
AU  - Job Morukileng
AU  - Richard Migisha
AU  - Benon Kwesiga
AU  - Paul Edward Okello
AU  - Lilian Bulage
AU  - Kami L. Smith
AU  - Joseph Ojwang
AU  - Sam Wasike
AU  - Stephen Balinandi
PY  - 2026
DA  - 2026/10/30
JO  - International Journal of Infectious Diseases
DO  - 10.1016/j.ijid.2026.109075
UR  - https://doi.org/10.1016/j.ijid.2026.109075
AB  - Objectives: On January 30, 2025, the Ministry of Health, Uganda (MoH), announced an outbreak of Sudan ebolavirus disease (SVD). We describe the epidemiological characteristics and transmission dynamics of the SVD outbreak in Uganda during January-April, 2025. Methods: SVD cases were identified using MoH case definitions and were classified as confirmed if positive on RT-qPCR or probable if an SVD-related death was reported with epidemiological linkage but without laboratory confirmation. Cases were identified through contact tracing, community and health facility alerts, and active search. Data were collected using a standard SVD case investigation form, including demographics, exposures and outcome. The effective reproductive number (Rt) was estimated using the EpiEstim package in R. Results: Fourteen cases were identified between January 30 and April 25, 2025: 12 (86%) were confirmed and two (14%) were probable; and five (36%) were health workers. The mean (range) age was 27 (0-50) years. Four cases died, a case fatality rate (CFR) of 29% (4/14). Most exposures were household (9[64%]) followed by healthcare-associated exposures (3[21%]). The index case was a health worker who died of a febrile illness 11 days after symptom onset, and postmortem samples returned positive for SUDV on the same day. A total of 534 contacts were monitored; of these, 454 (85%) were quarantined. Ten cases were known contacts; no secondary transmission occurred among these cases. The estimated Rt (interquartile range) was 1.1 (0.83-1.35). Conclusion: The outbreak had a low CFR and a low Rt, possibly due to early detection and swift identification, quarantine, and close monitoring of contacts.
SN  - 1201-9712
SN  - 1878-3511
ER  -