Recurrent Sarcoidosis Presenting With Bilateral Leg Edema: A Case Report
4 affiliations
- 1Midwestern University Chicago College of Osteopathic Medicine, Illinois, USA
- 2Department of the History of Medicine and Ethics, Erciyes University Faculty of Medicine, Kayseri, Türkiye
- 3Department of Internal Medicine, University of Central Florida College of Medicine, Florida, USA
- 4Lake Erie College of Osteopathic Medicine, Florida, USA
Abstract
Background: Bilateral lower extremity edema may serve as an early clinical manifestation of pulmonary sarcoidosis. Identifying sarcoidosis as the underlying cause can be challenging in patients with or without a prior history of the disease, as lower extremity edema is not typically considered part of its clinical spectrum.
Case Report: A 63-year-old man presented with a complex medical history, including non-Hodgkin lymphoma, bilateral renal cell carcinoma, colon cancer, and pleomorphic sarcoma of the upper extremity. He also had a history of recurrent pulmonary sarcoidosis. He reported a 6-month history of bilateral pitting lower extremity edema that developed several months before the onset of dyspnea.
Conclusion: In patients with multiple comorbidities, recognizing sarcoidosis as a potential cause of bilateral lower extremity edema requires careful exclusion of systemic and malignant etiologies. Sarcoidosis should be considered when more common causes have been excluded.
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BibTeX
@article{draves2026recurrent,
title = {{Recurrent Sarcoidosis Presenting With Bilateral Leg Edema: A Case Report}},
author = {Jacob Draves and Halil Tekiner and Steven H. Yale and Eileen S. Yale},
journal = {Journal of Clinical Practice and Research},
year = {2026},
month = jul,
doi = {10.14744/cpr.2026.82224},
url = {https://doi.org/10.14744/cpr.2026.82224},
note = {CC BY-NC 4.0},
}
RIS
TY - JOUR
TI - Recurrent Sarcoidosis Presenting With Bilateral Leg Edema: A Case Report
AU - Jacob Draves
AU - Halil Tekiner
AU - Steven H. Yale
AU - Eileen S. Yale
PY - 2026
DA - 2026/07/20
JO - Journal of Clinical Practice and Research
DO - 10.14744/cpr.2026.82224
UR - https://doi.org/10.14744/cpr.2026.82224
AB - Background: Bilateral lower extremity edema may serve as an early clinical manifestation of pulmonary sarcoidosis. Identifying sarcoidosis as the underlying cause can be challenging in patients with or without a prior history of the disease, as lower extremity edema is not typically considered part of its clinical spectrum. Case Report: A 63-year-old man presented with a complex medical history, including non-Hodgkin lymphoma, bilateral renal cell carcinoma, colon cancer, and pleomorphic sarcoma of the upper extremity. He also had a history of recurrent pulmonary sarcoidosis. He reported a 6-month history of bilateral pitting lower extremity edema that developed several months before the onset of dyspnea. Conclusion: In patients with multiple comorbidities, recognizing sarcoidosis as a potential cause of bilateral lower extremity edema requires careful exclusion of systemic and malignant etiologies. Sarcoidosis should be considered when more common causes have been excluded.
SN - 2980-2156
ER -