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PreprintCC BY 4.0arXiv

InfoAtlas: A Foundation Model for Zero-Shot Statistical Dependence Estimate

Abstract

Measuring statistical dependency between high-dimensional random variables is a fundamental task in data science and machine learning. Neural mutual information (MI) estimators offer a promising avenue, but they typically require costly iterative optimization for each new dataset, making them impractical for real-time applications. We present InfoAtlas, a foundation model-like architecture that eliminates this bottleneck by directly inferring MI in a single forward pass. Pretrained on large-scale synthetic data with rich dependence patterns, InfoAtlas learns to identify diverse dependence structures and predict MI directly from the dataset. Comprehensive experiments demonstrate that InfoAtlas matches state-of-the-art neural estimators in accuracy while achieving 100× speedup, can flexibly handle varying dimensions and sample sizes through a single unified model, and generalizes effectively to complex, real-world scenarios. By reformulating MI estimation as an inference task, InfoAtlas establishes a foundation for real-time dependency analysis.

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BibTeX
@misc{hu2026infoatlas,
  title = {{InfoAtlas: A Foundation Model for Zero-Shot Statistical Dependence Estimate}},
  author = {Zhengyang Hu and Yanzhi Chen and Hanxiang Ren and Qunsong Zeng and Youyi Zheng and Adrian Weller and Kaibin Huang and Yanchao Yang},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2606.00241},
  eprint = {2606.00241},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2606.00241},
  note = {CC BY 4.0},
}
RIS
TY  - UNPB
TI  - InfoAtlas: A Foundation Model for Zero-Shot Statistical Dependence Estimate
AU  - Zhengyang Hu
AU  - Yanzhi Chen
AU  - Hanxiang Ren
AU  - Qunsong Zeng
AU  - Youyi Zheng
AU  - Adrian Weller
AU  - Kaibin Huang
AU  - Yanchao Yang
PY  - 2026
DA  - 2026/09/12
PB  - arXiv
DO  - 10.48550/arxiv.2606.00241
UR  - https://arxiv.org/abs/2606.00241
AB  - Measuring statistical dependency between high-dimensional random variables is a fundamental task in data science and machine learning. Neural mutual information (MI) estimators offer a promising avenue, but they typically require costly iterative optimization for each new dataset, making them impractical for real-time applications. We present InfoAtlas, a foundation model-like architecture that eliminates this bottleneck by directly inferring MI in a single forward pass. Pretrained on large-scale synthetic data with rich dependence patterns, InfoAtlas learns to identify diverse dependence structures and predict MI directly from the dataset. Comprehensive experiments demonstrate that InfoAtlas matches state-of-the-art neural estimators in accuracy while achieving 100× speedup, can flexibly handle varying dimensions and sample sizes through a single unified model, and generalizes effectively to complex, real-world scenarios. By reformulating MI estimation as an inference task, InfoAtlas establishes a foundation for real-time dependency analysis.
ER  -