Women with severe postpartum hemorrhage have a decreased endogenous thrombin potential before delivery

Abstract

Essentials Severe postpartum hemorrhage is associated with maternal morbidity and mortality.

 We characterized coagulability of predelivery plasmas from pregnant women in a case-control study.

 Predelivery endogenous thrombin potential levels measured with the thrombin generation assay were reduced in women with severe postpartum hemorrhage.

 Further studies are needed to confirm these data and investigate potential underlying mechanisms.

Bilateral postpartum renal cortical necrosis complicated by peripartum cardiomyopathy after postpartum hemorrhage: a case report
Antoine Vanoost, Nicolas Mollet, Arthur Foulon +1
Journal of Gynecology Obstetrics and Human Reproduction1 Oct 2026Peer-reviewedCC BYFull textGeneral biology Obstetrics, gynaecology & paediatricsHAL
Family history of postpartum hemorrhage is a risk factor for postpartum hemorrhage after vaginal delivery: results from the French prospective multicenter Haemorrhages and Thromboembolic Venous Disease of the Postpartum cohort study
François Anouilh, Claire de Moreuil, Christophe Trémouilhac +19
American Journal of Obstetrics & Gynecology MFM16 Sep 2026Peer-reviewedCC BY-NC-ND 4.0Full text14 citedGeneral biology Epidemiology & public healthHAL
Loss of function of LprG-Rv1410c and MmpL11 homologues in Mycobacterium smegmatis leads to altered glycopeptidolipid profile and decreased cellular c-di-GMP levels during biofilm formation
M. Desroches, M. Coldren, L.-M. Nisbett
bioRxiv10 Sep 2026PreprintAll rights reservedFull textMicrobiologybioRxiv
On the Increased and Decreased Connectivity of the Demented Human Brain
Daniel Hegedus, Marton Barnabas Mora, Balint Varga +1
arXiv9 Sep 2026PreprintCC BY 4.0Full textNeurosciencearXiv
N1 neuraminidase monoclonal antibodies 2H08 and 3H03 have decreased binding and inhibition properties against H1N1 influenza viruses circulating after 2018
D. Bhavsar, E. Hermann, B. Monahan +4
bioRxiv26 Oct 2026PreprintCC BY-NC-NDFull textMicrobiologybioRxiv

Cite

BibTeX RIS

BibTeX

@article{moreuil2026women,
  title = {{Women with severe postpartum hemorrhage have a decreased endogenous thrombin potential before delivery}},
  author = {Claire de Moreuil and Yesim Dargaud and Christophe Nougier and Pierre-François Dupré and Christophe Trémouilhac and Delphine Le Joliff and Sylvain Rosec and Sandy Lucier and Ingrid Pabinger and Cihan Ay and Francis Couturaud and Brigitte Pan-Petesch},
  journal = {Journal of Thrombosis and Haemostasis},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jtha.2023.07.021},
  url = {https://univ-brest.hal.science/hal-05751509v1},
  note = {CC BY 4.0},
}

RIS

TY  - JOUR
TI  - Women with severe postpartum hemorrhage have a decreased endogenous thrombin potential before delivery
AU  - Claire de Moreuil
AU  - Yesim Dargaud
AU  - Christophe Nougier
AU  - Pierre-François Dupré
AU  - Christophe Trémouilhac
AU  - Delphine Le Joliff
AU  - Sylvain Rosec
AU  - Sandy Lucier
AU  - Ingrid Pabinger
AU  - Cihan Ay
AU  - Francis Couturaud
AU  - Brigitte Pan-Petesch
PY  - 2026
DA  - 2026/09/16
JO  - Journal of Thrombosis and Haemostasis
DO  - 10.1016/j.jtha.2023.07.021
UR  - https://univ-brest.hal.science/hal-05751509v1
AB  - Essentials Severe postpartum hemorrhage is associated with maternal morbidity and mortality.   We characterized coagulability of predelivery plasmas from pregnant women in a case-control study.   Predelivery endogenous thrombin potential levels measured with the thrombin generation assay were reduced in women with severe postpartum hemorrhage.   Further studies are needed to confirm these data and investigate potential underlying mechanisms.
SN  - 1538-7933
SN  - 1538-7836
ER  -

Abstract

Related

Cite