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Peer-reviewedCC BYJournal of applied clinical medical physics

Automated verification of source dwell position in lunar ovoid applicators.

6 affiliations
  1. 1University of Barcelona, Barcelona, Spain.
  2. 2Computer Vision and Robotics Institute, University of Girona, Girona, Spain.
  3. 3Medical Physics Section, Radiation Oncology Department, Hospital Clínic Barcelona, Barcelona, Spain.
  4. 4Radiation Protection Department, Hospital Clínic Barcelona, Barcelona, Spain.
  5. 5Infrastructure Management, Hospital Clínic Barcelona, Barcelona, Spain.
  6. 6Laboratory of Translational Genomics and Targeted therapies in Solid Tumors, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.

Abstract

Background

Accurate reconstruction of the source dwell positions in high-dose-rate (HDR) brachytherapy is essential for treatment quality. The Venezia™ gynaecological applicator, with its lunar-shaped ovoids, poses challenges because conventional dummy markers do not match the actual source path, introducing systematic uncertainties.Purpose

The aim of this work was to develop and demonstrate an automated, reproducible, and open-source software for autoradiographic verification of dwell positions in Venezia lunar ovoids, and to compare measured positions with manufacturer-provided applicator library data. This pipeline established a standardized approach for clinical commissioning and quality assurance (QA) workflows.Methods

A custom 3D-printed holder was designed to standardize autoradiograph acquisition using radiochromic films. An open-source Python pipeline, referred to as SPICA (Source Position Identification in Circular Applicators), was developed to process scanned films, isolate dwell position, and compute their coordinates with associated uncertainties. The code allows direct comparison between measured positions and manufacturer-provided applicator library data. We performed preliminary validation of the software by measuring the trajectory of an Ir-192 source for the 22 and 26 mm ovoids with a step size of 2.5 mm.Results

Mean discrepancies between measured and reference positions were 1.2 ± 0.5 and 1.5 ± 0.4 mm for the 22 and 26 mm ovoids, respectively, with a maximum deviation of 2.6 mm. Distal positions showed better agreement. These findings confirm that, in the tested applicator-afterloader combination, vendor libraries provide a generally reliable baseline but may exhibit systematic differences.Conclusions

The proposed methodology offers a practical, reproducible solution to improve source path verification while reducing manual intervention. It supports more robust commissioning and QA of complex applicators and using the coordinates calculated in the treatment planning software can potentially reduce geometric uncertainties in clinical cases. Individualized commissioning remains essential for applicators with complex geometries.

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BibTeX
@article{gubaubesalu2026automated,
  title = {{Automated verification of source dwell position in lunar ovoid applicators.}},
  author = {Miquel Gubau-Besalú and Adrià Casamitjana and Cristian Candela-Juan and Eduard Agusti-Camprubi and Gislè Segura-Roca and Gerard Trias and Antonio Herreros},
  journal = {Journal of applied clinical medical physics},
  year = {2026},
  month = oct,
  doi = {10.1002/acm2.70887},
  url = {https://europepmc.org/article/MED/42963831},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Automated verification of source dwell position in lunar ovoid applicators.
AU  - Miquel Gubau-Besalú
AU  - Adrià Casamitjana
AU  - Cristian Candela-Juan
AU  - Eduard Agusti-Camprubi
AU  - Gislè Segura-Roca
AU  - Gerard Trias
AU  - Antonio Herreros
PY  - 2026
DA  - 2026/10/30
JO  - Journal of applied clinical medical physics
DO  - 10.1002/acm2.70887
UR  - https://europepmc.org/article/MED/42963831
AB  - Background  Accurate reconstruction of the source dwell positions in high-dose-rate (HDR) brachytherapy is essential for treatment quality. The Venezia™ gynaecological applicator, with its lunar-shaped ovoids, poses challenges because conventional dummy markers do not match the actual source path, introducing systematic uncertainties.Purpose  The aim of this work was to develop and demonstrate an automated, reproducible, and open-source software for autoradiographic verification of dwell positions in Venezia lunar ovoids, and to compare measured positions with manufacturer-provided applicator library data. This pipeline established a standardized approach for clinical commissioning and quality assurance (QA) workflows.Methods  A custom 3D-printed holder was designed to standardize autoradiograph acquisition using radiochromic films. An open-source Python pipeline, referred to as SPICA (Source Position Identification in Circular Applicators), was developed to process scanned films, isolate dwell position, and compute their coordinates with associated uncertainties. The code allows direct comparison between measured positions and manufacturer-provided applicator library data. We performed preliminary validation of the software by measuring the trajectory of an Ir-192 source for the 22 and 26 mm ovoids with a step size of 2.5 mm.Results  Mean discrepancies between measured and reference positions were 1.2 ± 0.5 and 1.5 ± 0.4 mm for the 22 and 26 mm ovoids, respectively, with a maximum deviation of 2.6 mm. Distal positions showed better agreement. These findings confirm that, in the tested applicator-afterloader combination, vendor libraries provide a generally reliable baseline but may exhibit systematic differences.Conclusions  The proposed methodology offers a practical, reproducible solution to improve source path verification while reducing manual intervention. It supports more robust commissioning and QA of complex applicators and using the coordinates calculated in the treatment planning software can potentially reduce geometric uncertainties in clinical cases. Individualized commissioning remains essential for applicators with complex geometries.
SN  - 1526-9914
ER  -