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PreprintCC BY 4.0arXiv

Physiologically Informed Digital Auscultation for Pneumonia Detection in Long-term Care Residents

Abstract

Pneumonia is difficult to diagnose in older long-term care residents; multimorbidity and atypical presentations obscure signs, motivating operationally efficient objective testing. We analyzed multi-channel digital stethoscope recordings from 185 Japanese residents (73 pneumonia, 112 symptomatic without), using radiologist-confirmed chest X-rays and clinician diagnoses as supervisory signals that train convolutional neural networks, multimodal fusion, and channel-based variants with time-domain Grad-CAM interpretability. Models were evaluated with repeated patient-level cross-validation showing models with X-ray supervision outperformed clinician supervision (F1 0.729, accuracy 0.783 vs. F1 0.637, accuracy 0.711). Additionally, a three-channel selection protocol maintained performance (F1 0.736; accuracy 0.803), with two mid-thoracic sites ranking highest and Grad-CAM attention overlapping adventitious sounds. These findings indicate automated multi-channel lung-sound analysis can aid long-term care pneumonia diagnosis, with X-ray supervision being more reliable than clinical, and fewer channels preserving performance while lowering acquisition times.

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BibTeX
@misc{rasmussen2026physiologically,
  title = {{Physiologically Informed Digital Auscultation for Pneumonia Detection in Long-term Care Residents}},
  author = {Nicholas Rasmussen and Oleg Zaslavsky and Zih-Ling Wang and Hongyu Yu and Joelle Fathi and Kaibao Nie and Amil Khanzada and Tomoko Ito},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.27222},
  eprint = {2609.27222},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2609.27222},
  note = {CC BY 4.0},
}
RIS
TY  - UNPB
TI  - Physiologically Informed Digital Auscultation for Pneumonia Detection in Long-term Care Residents
AU  - Nicholas Rasmussen
AU  - Oleg Zaslavsky
AU  - Zih-Ling Wang
AU  - Hongyu Yu
AU  - Joelle Fathi
AU  - Kaibao Nie
AU  - Amil Khanzada
AU  - Tomoko Ito
PY  - 2026
DA  - 2026/09/23
PB  - arXiv
DO  - 10.48550/arxiv.2609.27222
UR  - https://arxiv.org/abs/2609.27222
AB  - Pneumonia is difficult to diagnose in older long-term care residents; multimorbidity and atypical presentations obscure signs, motivating operationally efficient objective testing. We analyzed multi-channel digital stethoscope recordings from 185 Japanese residents (73 pneumonia, 112 symptomatic without), using radiologist-confirmed chest X-rays and clinician diagnoses as supervisory signals that train convolutional neural networks, multimodal fusion, and channel-based variants with time-domain Grad-CAM interpretability. Models were evaluated with repeated patient-level cross-validation showing models with X-ray supervision outperformed clinician supervision (F1 0.729, accuracy 0.783 vs. F1 0.637, accuracy 0.711). Additionally, a three-channel selection protocol maintained performance (F1 0.736; accuracy 0.803), with two mid-thoracic sites ranking highest and Grad-CAM attention overlapping adventitious sounds. These findings indicate automated multi-channel lung-sound analysis can aid long-term care pneumonia diagnosis, with X-ray supervision being more reliable than clinical, and fewer channels preserving performance while lowering acquisition times.
ER  -