Association Between Early Pain and Miniscrew-Related Oral Impact After Orthodontic Miniscrew Placement: A Prospective Cohort Study
- 1Department of Orthodontics, College of Dentistry, University of Sulaimani, Sulaimani P.O. Box 1124-30, Iraq
Abstract
Background/Objectives: Evidence integrating patient-reported outcomes with the clinical performance of orthodontic miniscrews remains limited. This study evaluated pain, miniscrew-related oral impact, and six-month clinical outcomes following miniscrew placement. Methods: In this single-centre prospective observational cohort, 111 patients were screened, 104 were enrolled, and 100 patients receiving 270 clinically indicated miniscrews contributed complete data. Pain was assessed using a visual analogue scale immediately after placement, at 24 h, and at one week. A preliminary eight-item miniscrew-related oral-impact questionnaire was completed at one week. Analyses included the Friedman test with Holm-adjusted pairwise comparisons, Spearman correlations, and logistic generalised estimating equations (GEEs) accounting for within-patient clustering. Results: Median pain decreased from 6.0 (IQR, 3–8) immediately after placement to 4.0 (IQR, 0–7.25) at 24 h and 0.0 (IQR, 0–2) at one week (p < 0.001; Kendall’s W = 0.568; pairwise r = 0.366–0.758). Analgesics were used by 57% of participants. The mean oral-impact score was 6.08 ± 5.92 on a 0–32 scale. Greater immediate post-placement pain was associated with higher oral-impact scores (ρ = 0.431; p < 0.001). At six months, 250 of 270 miniscrews were successful (92.6%). At the miniscrew level, soft-tissue injury and localised inflammation affected 7.8% and 4.4%, respectively. No examined factor was reliably associated with failure in the clustered GEE model. At the patient level, 78% were satisfied or very satisfied, and 92% would recommend the procedure. Conclusions: Pain decreased substantially within one week, while greater early pain was associated with less favourable oral-impact scores. A 92.6% six-month success rate and favourable patient acceptance were observed. The questionnaire requires further validation, and the exploratory failure estimates require confirmation.
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BibTeX
@article{ismail2026association,
title = {{Association Between Early Pain and Miniscrew-Related Oral Impact After Orthodontic Miniscrew Placement: A Prospective Cohort Study}},
author = {Hadi M. Ismail},
journal = {Journal of Clinical Medicine},
year = {2026},
month = oct,
doi = {10.3390/jcm15207852},
url = {https://www.mdpi.com/2077-0383/15/20/7852},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Association Between Early Pain and Miniscrew-Related Oral Impact After Orthodontic Miniscrew Placement: A Prospective Cohort Study
AU - Hadi M. Ismail
PY - 2026
DA - 2026/10/12
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15207852
UR - https://www.mdpi.com/2077-0383/15/20/7852
AB - Background/Objectives: Evidence integrating patient-reported outcomes with the clinical performance of orthodontic miniscrews remains limited. This study evaluated pain, miniscrew-related oral impact, and six-month clinical outcomes following miniscrew placement. Methods: In this single-centre prospective observational cohort, 111 patients were screened, 104 were enrolled, and 100 patients receiving 270 clinically indicated miniscrews contributed complete data. Pain was assessed using a visual analogue scale immediately after placement, at 24 h, and at one week. A preliminary eight-item miniscrew-related oral-impact questionnaire was completed at one week. Analyses included the Friedman test with Holm-adjusted pairwise comparisons, Spearman correlations, and logistic generalised estimating equations (GEEs) accounting for within-patient clustering. Results: Median pain decreased from 6.0 (IQR, 3–8) immediately after placement to 4.0 (IQR, 0–7.25) at 24 h and 0.0 (IQR, 0–2) at one week (p < 0.001; Kendall’s W = 0.568; pairwise r = 0.366–0.758). Analgesics were used by 57% of participants. The mean oral-impact score was 6.08 ± 5.92 on a 0–32 scale. Greater immediate post-placement pain was associated with higher oral-impact scores (ρ = 0.431; p < 0.001). At six months, 250 of 270 miniscrews were successful (92.6%). At the miniscrew level, soft-tissue injury and localised inflammation affected 7.8% and 4.4%, respectively. No examined factor was reliably associated with failure in the clustered GEE model. At the patient level, 78% were satisfied or very satisfied, and 92% would recommend the procedure. Conclusions: Pain decreased substantially within one week, while greater early pain was associated with less favourable oral-impact scores. A 92.6% six-month success rate and favourable patient acceptance were observed. The questionnaire requires further validation, and the exploratory failure estimates require confirmation.
SN - 2077-0383
ER -