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Peer-reviewedCC BYJournal of Electrical Bioimpedance

Electromagnetic validation of a multichannel coplanar four-electrode bioimpedance sensing platform for perfused 3D tumor-on-chip systems

  1. 1Univ. Lille, Inserm, CHU Lille, CNRS, U1366-UMR9020 – CRCLille, F-59000Lille, France
  2. 2Univ. Lille, CNRS, Inserm, CHU Lille, IPL, U1019-UMR9017– CIIL, F-59000Lille, France
  3. 3Department of Physics, University of Oslo, Oslo, Norway

Abstract

Three-dimensional tumor-on-chip systems better reproduce the spatial organization of tumor cells within extracellular-matrix-based microenvironments than conventional two-dimensional cultures, yet their integration with quantitative, non-destructive monitoring tools remains limited. Electrical bioimpedance provides a label-free approach for real-time assessment of living 3D tissues, but its implementation in perfused millimeter-scale microfluidic environments requires rigorous electrical and geometrical validation.

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BibTeX
@article{felix2026electromagnetic,
  title = {{Electromagnetic validation of a multichannel coplanar four-electrode bioimpedance sensing platform for perfused 3D tumor-on-chip systems}},
  author = {Royer Félix and Meynard Thomas and Houssier Robin and Vicogne Jérôme and Martinsen Ørjan G. and Van Seuningen Isabelle and Senez Vincent},
  journal = {Journal of Electrical Bioimpedance},
  year = {2026},
  month = oct,
  doi = {10.2478/joeb-2026-0015},
  url = {https://doi.org/10.2478/joeb-2026-0015},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Electromagnetic validation of a multichannel coplanar four-electrode bioimpedance sensing platform for perfused 3D tumor-on-chip systems
AU  - Royer Félix
AU  - Meynard Thomas
AU  - Houssier Robin
AU  - Vicogne Jérôme
AU  - Martinsen Ørjan G.
AU  - Van Seuningen Isabelle
AU  - Senez Vincent
PY  - 2026
DA  - 2026/10/26
JO  - Journal of Electrical Bioimpedance
DO  - 10.2478/joeb-2026-0015
UR  - https://doi.org/10.2478/joeb-2026-0015
AB  - Three-dimensional tumor-on-chip systems better reproduce the spatial organization of tumor cells within extracellular-matrix-based microenvironments than conventional two-dimensional cultures, yet their integration with quantitative, non-destructive monitoring tools remains limited. Electrical bioimpedance provides a label-free approach for real-time assessment of living 3D tissues, but its implementation in perfused millimeter-scale microfluidic environments requires rigorous electrical and geometrical validation.
SN  - 1891-5469
ER  -