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Peer-reviewedCC BY 4.0Phytochemistry Letters

An unusual acyclic nor-triterpene derivative from Lacrymaria lacrymabunda mushroom active against methicillin-resistant Staphylococcus aureus (MRSA)

  • Théo Ozga
  • Franck Cantet
  • Jean-Michel Bellanger
  • Matteo Bonazzi
  • Aurélie Urbain
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Abstract

An unusual linear nor-triterpene derivative named lacrymaric acid (1) was isolated from Lacrymaria lacrymabunda caps. This compound was revealed in TLC-bioautography as antibacterial against various Staphylococcus aureus strains, including methicillin-resistant clinical isolates (MRSA). The structure of 1 was unambiguously elucidated by spectroscopic analyses (HR-ESI-MS, 1D and 2D NMR) as an acyclic carboxylated nor-triterpene putatively derived from squalene.

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Cite

BibTeXRIS
BibTeX
@article{ozga2026unusual,
  title = {{An unusual acyclic nor-triterpene derivative from Lacrymaria lacrymabunda mushroom active against methicillin-resistant Staphylococcus aureus (MRSA)}},
  author = {Théo Ozga and Franck Cantet and Jean-Michel Bellanger and Matteo Bonazzi and Aurélie Urbain},
  journal = {Phytochemistry Letters},
  year = {2026},
  month = sep,
  doi = {10.1016/j.phytol.2026.104226},
  url = {https://hal.science/hal-05743556v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - An unusual acyclic nor-triterpene derivative from Lacrymaria lacrymabunda mushroom active against methicillin-resistant Staphylococcus aureus (MRSA)
AU  - Théo Ozga
AU  - Franck Cantet
AU  - Jean-Michel Bellanger
AU  - Matteo Bonazzi
AU  - Aurélie Urbain
PY  - 2026
DA  - 2026/09/09
JO  - Phytochemistry Letters
DO  - 10.1016/j.phytol.2026.104226
UR  - https://hal.science/hal-05743556v1
AB  - An unusual linear nor-triterpene derivative named lacrymaric acid (1) was isolated from Lacrymaria lacrymabunda caps. This compound was revealed in TLC-bioautography as antibacterial against various Staphylococcus aureus strains, including methicillin-resistant clinical isolates (MRSA). The structure of 1 was unambiguously elucidated by spectroscopic analyses (HR-ESI-MS, 1D and 2D NMR) as an acyclic carboxylated nor-triterpene putatively derived from squalene.
SN  - 1874-3900
ER  -