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Peer-reviewedCC BY-NC-NDInternal Medicine

Clinical and Microbiological Characteristics of Patients with Desulfovibrio spp. Bacteremia in a Japanese Tertiary Hospital: A Case Series

Abstract

We retrospectively analyzed nine cases of Desulfovibrio spp. bacteremia at a Japanese tertiary hospital: five cases were caused by D. fairfieldensis and four by D. desulfuricans (three MB and one Essex 6 genotype). Intra-abdominal infection was the most common source of infection. Only the D. desulfuricans Essex 6 isolate was identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The remaining isolates required 16S rRNA gene sequencing. Clinicians should suspect Desulfovibrio spp. infection when curved Gram-negative bacilli are recovered from anaerobic blood cultures after 3-5 days because these species often cannot be identified by MALDI-TOF MS.

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BibTeX
@article{kitagawa2026clinical,
  title = {{Clinical and Microbiological Characteristics of Patients with Desulfovibrio spp. Bacteremia in a Japanese Tertiary Hospital: A Case Series}},
  author = {Hiroki Kitagawa and Kayoko Tadera and Keitaro Omori and Takuji Omoto and Toshihito Nomura and Norifumi Shigemoto and Hiroki Ohge},
  journal = {Internal Medicine},
  year = {2026},
  month = nov,
  doi = {10.2169/internalmedicine.6606-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/21/65_6606-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Clinical and Microbiological Characteristics of Patients with Desulfovibrio spp. Bacteremia in a Japanese Tertiary Hospital: A Case Series
AU  - Hiroki Kitagawa
AU  - Kayoko Tadera
AU  - Keitaro Omori
AU  - Takuji Omoto
AU  - Toshihito Nomura
AU  - Norifumi Shigemoto
AU  - Hiroki Ohge
PY  - 2026
DA  - 2026/11/01
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6606-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/21/65_6606-25/_article
AB  - We retrospectively analyzed nine cases of Desulfovibrio spp. bacteremia at a Japanese tertiary hospital: five cases were caused by D. fairfieldensis and four by D. desulfuricans (three MB and one Essex 6 genotype). Intra-abdominal infection was the most common source of infection. Only the D. desulfuricans Essex 6 isolate was identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The remaining isolates required 16S rRNA gene sequencing. Clinicians should suspect Desulfovibrio spp. infection when curved Gram-negative bacilli are recovered from anaerobic blood cultures after 3-5 days because these species often cannot be identified by MALDI-TOF MS.
SN  - 1349-7235
SN  - 0918-2918
ER  -