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Peer-reviewedCC BY-NC-ND 4.0International Journal of Surgery Case Reports

Metachronous cutaneous metastasis from right-sided colon cancer at a drain site: a case report and literature review

  • Hazem Alouani1
  • Salsabil Nasri1
  • Amine Ben Safta1
  • Imen Samâali1
  • Hichem Jerraya1
  • Ramzi Nouira1
  1. 1Department of General Surgery B, Charles Nicolle Hospital, Tunis, Tunisia
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Abstract

Introduction:: Cutaneous metastases from colorectal cancer (CRC) are rare and often indicate advanced disease. This case report highlights an uncommon pattern of recurrence from right-sided colon cancer and reviews the pertinent literature.

Case presentation:: A 57-year-old woman with a history of emergency right colectomy for perforated colonic adenocarcinoma developed a cutaneous nodule, rapidly increasing in size and measuring 3 × 4 cm, at the site of a previous drain 6 months after surgery. Biopsy confirmed metastatic adenocarcinoma. Apart from the cutaneous metastasis, imaging showed a deep retroperitoneal mass that did not communicate with the cutaneous nodule and no other visceral metastases. Systemic chemotherapy was reinitiated with bevacizumab. Due to refractory bleeding and transfusion-dependent anemia, surgical excision of the cutaneous lesion was performed, improving the patient’s quality of life.

Clinical discussion:: Cutaneous metastases from CRC are unusual and generally associated with poor prognosis. Their management remains palliative in most cases. Drain-site metastasis is particularly rare and may reflect tumor cell seeding.

Conclusion:: Vigilance for nodular skin lesions in post-operative CRC patients is crucial. Prompt biopsy and imaging facilitate early diagnosis and appropriate management.

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Cite

BibTeXRIS
BibTeX
@article{alouani2026metachronous,
  title = {{Metachronous cutaneous metastasis from right-sided colon cancer at a drain site: a case report and literature review}},
  author = {Hazem Alouani and Salsabil Nasri and Amine Ben Safta and Imen Samâali and Hichem Jerraya and Ramzi Nouira},
  journal = {International Journal of Surgery Case Reports},
  year = {2026},
  month = oct,
  doi = {10.1097/rc9.0000000000001200},
  url = {https://doi.org/10.1097/rc9.0000000000001200},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Metachronous cutaneous metastasis from right-sided colon cancer at a drain site: a case report and literature review
AU  - Hazem Alouani
AU  - Salsabil Nasri
AU  - Amine Ben Safta
AU  - Imen Samâali
AU  - Hichem Jerraya
AU  - Ramzi Nouira
PY  - 2026
DA  - 2026/10/22
JO  - International Journal of Surgery Case Reports
DO  - 10.1097/rc9.0000000000001200
UR  - https://doi.org/10.1097/rc9.0000000000001200
AB  - Introduction:: Cutaneous metastases from colorectal cancer (CRC) are rare and often indicate advanced disease. This case report highlights an uncommon pattern of recurrence from right-sided colon cancer and reviews the pertinent literature.  Case presentation:: A 57-year-old woman with a history of emergency right colectomy for perforated colonic adenocarcinoma developed a cutaneous nodule, rapidly increasing in size and measuring 3 × 4 cm, at the site of a previous drain 6 months after surgery. Biopsy confirmed metastatic adenocarcinoma. Apart from the cutaneous metastasis, imaging showed a deep retroperitoneal mass that did not communicate with the cutaneous nodule and no other visceral metastases. Systemic chemotherapy was reinitiated with bevacizumab. Due to refractory bleeding and transfusion-dependent anemia, surgical excision of the cutaneous lesion was performed, improving the patient’s quality of life.  Clinical discussion:: Cutaneous metastases from CRC are unusual and generally associated with poor prognosis. Their management remains palliative in most cases. Drain-site metastasis is particularly rare and may reflect tumor cell seeding.  Conclusion:: Vigilance for nodular skin lesions in post-operative CRC patients is crucial. Prompt biopsy and imaging facilitate early diagnosis and appropriate management.
SN  - 2210-2612
ER  -