Peer-reviewedCC BY-NC-NDInternal Medicine
A Temporal Pole Lesion in Neuronal Intranuclear Inclusion Disease: A Case Report
Abstract
An 81-year-old woman was transferred to our hospital due to a consciousness disorder. MRI of her cranium revealed white matter lesions and lesions in the cerebellar paravermis, splenium of the corpus callosum, and a left temporal pole on fluid-attenuated inversion recovery (FLAIR) sequences. Diffusion-weighted imaging (DWI) revealed hyperintensity at the left frontal corticomedullary junction of the brain. She was diagnosed with neuronal intranuclear inclusion disease (NIID) via a skin biopsy and genetic analysis. These lesions were evident before the DWI hyperintensity was clear. When a lesion in the temporal pole is observed, then NIID should be considered in the differential diagnosis.
Related
- Spatiotemporal Analysis of Intranuclear Inclusion Body and Virus Formation in Human Adenovirus Type 5-Infected Cells
- Accumulation of FAM98B and tRNA-Splicing Ligase Complex Proteins in Neuronal Intranuclear Inclusions in Spinocerebellar ataxia type 4.
- Longitudinal Imaging in a Mouse Model of Focal Cortical Dysplasia Reveals Lesion Expansion and Loss of Pre-Discharge Neuronal Recruitment
- Temporal and spatial alterations in GPi neuronal encoding might contribute to slow down movement in Parkinsonian monkeys
- Top-down semantic predictions align phonetic neuronal dynamics in human superior temporal gyrus
BibTeX
@article{inaba2026temporal,
title = {{A Temporal Pole Lesion in Neuronal Intranuclear Inclusion Disease: A Case Report}},
author = {Tomoya Inaba and Yoshinori Hirata and Hidehiro Ishikawa and Asako Tamura and Jun Sone and Akihiro Shindo},
journal = {Internal Medicine},
year = {2026},
month = jul,
doi = {10.2169/internalmedicine.7301-26},
url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7301-26/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - A Temporal Pole Lesion in Neuronal Intranuclear Inclusion Disease: A Case Report
AU - Tomoya Inaba
AU - Yoshinori Hirata
AU - Hidehiro Ishikawa
AU - Asako Tamura
AU - Jun Sone
AU - Akihiro Shindo
PY - 2026
DA - 2026/07/04
JO - Internal Medicine
DO - 10.2169/internalmedicine.7301-26
UR - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7301-26/_article
AB - An 81-year-old woman was transferred to our hospital due to a consciousness disorder. MRI of her cranium revealed white matter lesions and lesions in the cerebellar paravermis, splenium of the corpus callosum, and a left temporal pole on fluid-attenuated inversion recovery (FLAIR) sequences. Diffusion-weighted imaging (DWI) revealed hyperintensity at the left frontal corticomedullary junction of the brain. She was diagnosed with neuronal intranuclear inclusion disease (NIID) via a skin biopsy and genetic analysis. These lesions were evident before the DWI hyperintensity was clear. When a lesion in the temporal pole is observed, then NIID should be considered in the differential diagnosis.
SN - 1349-7235
SN - 0918-2918
ER -