Investigating the association between osteoarthritis and cardiovascular disease using a standardized cardiovascular health assessment tool in a nationwide health survey
- 1Department of Orthopedic Surgery, College of Medicine, St. Vincent’s Hospital, The Catholic University of Korea
- 2Department of Statistics and Actuarial Science, Soongsil University
- 3Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, St. Vincent’s Hospital, The Catholic University of Korea
Abstract
Osteoarthritis (OA) and cardiovascular disease (CVD) are thought to be interrelated, but the nature of their connection remains unclear. We examined the association between OA and cardiovascular health (CVH) using Life’s Essential 8 (LE8), a standardized CVH assessment tool. We conducted a population-based cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey collected between 2014 and 2021, comprising 35,001 adults aged 19 years or older. LE8 scores were compared by OA status, which was determined from self-reported physician diagnosis, and logistic regression analysis was used to estimate the odds of OA across CVH grades. In this cross-sectional analysis, higher CVH was associated with lower odds of OA. After adjustment for age, sex, and socioeconomic status, individuals with moderate or high CVH had approximately 19% and 40% lower odds of OA than those with low CVH (OR 0.81, 95% CI 0.73–0.91; OR 0.60, 95% CI 0.48–0.74; P < 0.001). The difference was primarily observed in the health factors domain, particularly body mass index (BMI) and blood pressure, whereas the health behaviors domain showed no consistent association after adjustment. Overall, poorer CVH was associated with a higher likelihood of coexisting OA, with differences most evident in BMI and blood pressure.
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BibTeX
@article{choi2026investigating,
title = {{Investigating the association between osteoarthritis and cardiovascular disease using a standardized cardiovascular health assessment tool in a nationwide health survey}},
author = {Youn-Ho Choi and Yoon-Chung Kim and Kyung-Do Han and Gyu-Na Lee and Hae Seok Koh and DoJoon Park and Woojin Lee and Seung-Hyun Ko},
journal = {Scientific Reports},
year = {2026},
month = sep,
doi = {10.1038/s41598-026-71255-1},
url = {https://doi.org/10.1038/s41598-026-71255-1},
note = {CC BY},
}
RIS
TY - JOUR
TI - Investigating the association between osteoarthritis and cardiovascular disease using a standardized cardiovascular health assessment tool in a nationwide health survey
AU - Youn-Ho Choi
AU - Yoon-Chung Kim
AU - Kyung-Do Han
AU - Gyu-Na Lee
AU - Hae Seok Koh
AU - DoJoon Park
AU - Woojin Lee
AU - Seung-Hyun Ko
PY - 2026
DA - 2026/09/01
JO - Scientific Reports
DO - 10.1038/s41598-026-71255-1
UR - https://doi.org/10.1038/s41598-026-71255-1
AB - Osteoarthritis (OA) and cardiovascular disease (CVD) are thought to be interrelated, but the nature of their connection remains unclear. We examined the association between OA and cardiovascular health (CVH) using Life’s Essential 8 (LE8), a standardized CVH assessment tool. We conducted a population-based cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey collected between 2014 and 2021, comprising 35,001 adults aged 19 years or older. LE8 scores were compared by OA status, which was determined from self-reported physician diagnosis, and logistic regression analysis was used to estimate the odds of OA across CVH grades. In this cross-sectional analysis, higher CVH was associated with lower odds of OA. After adjustment for age, sex, and socioeconomic status, individuals with moderate or high CVH had approximately 19% and 40% lower odds of OA than those with low CVH (OR 0.81, 95% CI 0.73–0.91; OR 0.60, 95% CI 0.48–0.74; P < 0.001). The difference was primarily observed in the health factors domain, particularly body mass index (BMI) and blood pressure, whereas the health behaviors domain showed no consistent association after adjustment. Overall, poorer CVH was associated with a higher likelihood of coexisting OA, with differences most evident in BMI and blood pressure.
SN - 2045-2322
ER -