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Peer-reviewedCC BY-NC-ND 4.0American Journal of Ophthalmology Case Reports

Membrane stripping alone for suspected ocular argyrosis: A novel therapeutic approach

  1. 1Department of Ophthalmology (Guru Nanak Eye Centre), Maulana Azad Medical College, New Delhi, India

Abstract

Purpose: To report two cases of suspected ocular argyrosis and discuss their management.

Background: Ocular argyrosis is a rare condition resulting from chronic silver exposure, typically manifesting as grayish corneal deposits at the level of Descemet's membrane and conjunctiva. It is often associated with systemic argyria in individuals with occupational exposure to silver compounds. Current literature lacks consensus on treatment, with most cases reporting long term retinal damage due to the condition. Vision loss is associated with the concurrent macular damage, and cataractous lens changes. In this report, we describe the clinical presentation, histopathology, and surgical management of ocular argyrosis.

Conclusion: Conservative approach like a Membrane stripping alone for visual rehabilitation might work in cases of ocular argryrosis, eliminating the need for a keratoplasty

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BibTeX
@article{arora2026membrane,
  title = {{Membrane stripping alone for suspected ocular argyrosis: A novel therapeutic approach}},
  author = {Ritu Arora and Avani Hariani and Parul Jain and Isha Gupta},
  journal = {American Journal of Ophthalmology Case Reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.ajoc.2026.102695},
  url = {https://doi.org/10.1016/j.ajoc.2026.102695},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Membrane stripping alone for suspected ocular argyrosis: A novel therapeutic approach
AU  - Ritu Arora
AU  - Avani Hariani
AU  - Parul Jain
AU  - Isha Gupta
PY  - 2026
DA  - 2026/10/25
JO  - American Journal of Ophthalmology Case Reports
DO  - 10.1016/j.ajoc.2026.102695
UR  - https://doi.org/10.1016/j.ajoc.2026.102695
AB  - Purpose: To report two cases of suspected ocular argyrosis and discuss their management.  Background: Ocular argyrosis is a rare condition resulting from chronic silver exposure, typically manifesting as grayish corneal deposits at the level of Descemet's membrane and conjunctiva. It is often associated with systemic argyria in individuals with occupational exposure to silver compounds. Current literature lacks consensus on treatment, with most cases reporting long term retinal damage due to the condition. Vision loss is associated with the concurrent macular damage, and cataractous lens changes. In this report, we describe the clinical presentation, histopathology, and surgical management of ocular argyrosis.  Conclusion: Conservative approach like a Membrane stripping alone for visual rehabilitation might work in cases of ocular argryrosis, eliminating the need for a keratoplasty
SN  - 2451-9936
ER  -