Peer-reviewedCC BY-NC-NDTaiwan Journal of Ophthalmology
Clinical observations of features in spectrum domain optical coherence tomography of amiodarone-induced retinopathy: Two case presentation
Abstract
Amiodarone is a class III anti-arrhythmic medication, which may result in possible ocular adverse effects. Amiodarone-associated retinopathy is infrequently perceived but is a potentially vision-threatening condition. We presented two rare cases of amiodarone-associated retinopathy. Their spectrum domain optical coherence tomography (SD-OCT) depicted loss of inner segment/outer segment (IS/OS) and cone outer segment tips (COSTs) lines at the macular region, sparing the external limiting membrane. One case exhibited additional hyperreflective spots at the subretinal layer on SD-OCT. Following the discontinuation of amiodarone and the administration of vitamin C eye drops, a partial recovery in the IS/OS and COST lines was observed.
Related
- Diagnostic capability of perimetry and optical coherence tomography based retinal thickness measurements in diabetic patients with no or mild retinopathy
- Impact of Optical Coherence Tomography Angiography Scan Protocols on Quantitative Microvascular Biomarkers in Diabetic Retinopathy.
- Comparison of Optical Coherence Tomography Biomarkers in Nonproliferative and Proliferative Diabetic Retinopathy: Marmasia Study Group Report No. 2
- Retained lens fragments obscured by bullous keratopathy: Anterior segment optical coherence tomography before and after endothelial keratoplasty
- Serial bedside retinal optical coherence tomography angiography in sepsis associated circulatory dysfunction
BibTeX
@article{chang2026clinical,
title = {{Clinical observations of features in spectrum domain optical coherence tomography of amiodarone-induced retinopathy: Two case presentation}},
author = {Chun Pao Chang and Hung-Chi Chen and An-Ning Chao and Laura Liu and Kuan-Jen Chen and Yi-Hsing Chen},
journal = {Taiwan Journal of Ophthalmology},
year = {2026},
month = jul,
doi = {10.4103/tjo.tjo-d-23-00151},
url = {https://doi.org/10.4103/tjo.tjo-d-23-00151},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Clinical observations of features in spectrum domain optical coherence tomography of amiodarone-induced retinopathy: Two case presentation
AU - Chun Pao Chang
AU - Hung-Chi Chen
AU - An-Ning Chao
AU - Laura Liu
AU - Kuan-Jen Chen
AU - Yi-Hsing Chen
PY - 2026
DA - 2026/07/01
JO - Taiwan Journal of Ophthalmology
DO - 10.4103/tjo.tjo-d-23-00151
UR - https://doi.org/10.4103/tjo.tjo-d-23-00151
AB - Amiodarone is a class III anti-arrhythmic medication, which may result in possible ocular adverse effects. Amiodarone-associated retinopathy is infrequently perceived but is a potentially vision-threatening condition. We presented two rare cases of amiodarone-associated retinopathy. Their spectrum domain optical coherence tomography (SD-OCT) depicted loss of inner segment/outer segment (IS/OS) and cone outer segment tips (COSTs) lines at the macular region, sparing the external limiting membrane. One case exhibited additional hyperreflective spots at the subretinal layer on SD-OCT. Following the discontinuation of amiodarone and the administration of vitamin C eye drops, a partial recovery in the IS/OS and COST lines was observed.
SN - 2211-5056
SN - 2211-5072
ER -