Phase Image Display Settings for Paramagnetic Rim Lesion Detection in Multiple Sclerosis: A Practical Guide
Abstract
The 2024 revisions of the McDonald criteria incorporate the paramagnetic rim lesion (PRL) into the diagnostic framework of multiple sclerosis, and PRL evolution is increasingly recognized as a marker of disease progression. PRLs are detected on phase images of susceptibility-sensitive sequences, but their visibility depends critically on display settings. Current consensus recommendations provide detailed guidance on acquisition parameters yet do not address the phase-image window/level applied at the reading workstation; an inappropriate phase window can render rims invisible. We discuss practical tips for reliable PRL detection, including awareness of vendor-specific phase conventions, windowing to optimize conspicuity, and hands-on training, to support accurate and reproducible PRL assessment in routine clinical practice.
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BibTeX
@article{hagiwara2026phase,
title = {{Phase Image Display Settings for Paramagnetic Rim Lesion Detection in Multiple Sclerosis: A Practical Guide}},
author = {Akifumi Hagiwara and Yuki Sonoda and Yuji Tomizawa and Koji Shinoda and Isamu Takai and Yasunobu Hoshino and Junko Kikuta and Taku Hatano and Koji Kamagata},
journal = {Magnetic Resonance in Medical Sciences},
year = {2026},
month = oct,
doi = {10.2463/mrms.e.2026-2000},
url = {https://www.jstage.jst.go.jp/article/mrms/25/4/25_e.2026-2000/_article},
note = {CC BY},
}
RIS
TY - JOUR
TI - Phase Image Display Settings for Paramagnetic Rim Lesion Detection in Multiple Sclerosis: A Practical Guide
AU - Akifumi Hagiwara
AU - Yuki Sonoda
AU - Yuji Tomizawa
AU - Koji Shinoda
AU - Isamu Takai
AU - Yasunobu Hoshino
AU - Junko Kikuta
AU - Taku Hatano
AU - Koji Kamagata
PY - 2026
DA - 2026/10/16
JO - Magnetic Resonance in Medical Sciences
DO - 10.2463/mrms.e.2026-2000
UR - https://www.jstage.jst.go.jp/article/mrms/25/4/25_e.2026-2000/_article
AB - The 2024 revisions of the McDonald criteria incorporate the paramagnetic rim lesion (PRL) into the diagnostic framework of multiple sclerosis, and PRL evolution is increasingly recognized as a marker of disease progression. PRLs are detected on phase images of susceptibility-sensitive sequences, but their visibility depends critically on display settings. Current consensus recommendations provide detailed guidance on acquisition parameters yet do not address the phase-image window/level applied at the reading workstation; an inappropriate phase window can render rims invisible. We discuss practical tips for reliable PRL detection, including awareness of vendor-specific phase conventions, windowing to optimize conspicuity, and hands-on training, to support accurate and reproducible PRL assessment in routine clinical practice.
SN - 1880-2206
SN - 1347-3182
ER -