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Peer-reviewedCC BYFrontiers in Gastroenterology

Hepatic small vessel neoplasm, a first case report in a liver transplant recipient

  • Afaf Awad Y. Ahmad1
  • Michael Craughwell2
  • Lindsey Clarke2
  • Niamh Nolan2
  • Audrey Dillon1
  • Zita Galvin1
  1. 1The National Liver Transplant Unit, St. Vincent’s University Hospital, Dublin, Ireland
  2. 2Histopathology Department, St. Vincent’s University Hospital, Dublin, Ireland
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Abstract

Hepatic small vessel neoplasm (HSVN) is a recently recognized vascular tumor of the liver that behaves in a largely indolent fashion but carries uncertain malignant potential. Unlike hepatic angiosarcoma, HSVN lacks marked cytologic atypia and does not demonstrate diffuse p53, GLUT1, or c-Myc overexpression. We describe what appears to be the first reported case of HSVN arising in a liver allograft, highlighting diagnostic challenges and management considerations in a transplant recipient.

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Cite

BibTeXRIS
BibTeX
@article{ahmad2026hepatic,
  title = {{Hepatic small vessel neoplasm, a first case report in a liver transplant recipient}},
  author = {Afaf Awad Y. Ahmad and Michael Craughwell and Lindsey Clarke and Niamh Nolan and Audrey Dillon and Zita Galvin},
  journal = {Frontiers in Gastroenterology},
  year = {2026},
  month = oct,
  doi = {10.3389/fgstr.2026.1956520},
  url = {https://doi.org/10.3389/fgstr.2026.1956520},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Hepatic small vessel neoplasm, a first case report in a liver transplant recipient
AU  - Afaf Awad Y. Ahmad
AU  - Michael Craughwell
AU  - Lindsey Clarke
AU  - Niamh Nolan
AU  - Audrey Dillon
AU  - Zita Galvin
PY  - 2026
DA  - 2026/10/26
JO  - Frontiers in Gastroenterology
DO  - 10.3389/fgstr.2026.1956520
UR  - https://doi.org/10.3389/fgstr.2026.1956520
AB  - Hepatic small vessel neoplasm (HSVN) is a recently recognized vascular tumor of the liver that behaves in a largely indolent fashion but carries uncertain malignant potential. Unlike hepatic angiosarcoma, HSVN lacks marked cytologic atypia and does not demonstrate diffuse p53, GLUT1, or c-Myc overexpression. We describe what appears to be the first reported case of HSVN arising in a liver allograft, highlighting diagnostic challenges and management considerations in a transplant recipient.
SN  - 2813-1169
ER  -