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PreprintCC BYbioRxiv

Awake sharp-wave ripples coincide with rhythmic cortical synchronization

  • T. H. Lim
  • X. Zhang1
  1. 1University of Zurich
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Abstract

Analysis of the Allen Institute Visual Coding Neuropixels dataset revealed a ~5 Hz synchronization of visual cortical activity in awake, immobile mice. During bouts of this rhythm, synchronized cortical bursts coincided with changes in the occurrence of sharp-wave ripples (SWRs) and dentate spikes and in SWR properties. Cortical synchronization, SWRs, and dentate spikes were also coordinated with slower pupil-size fluctuation, revealing that awake SWRs are embedded within nested brainwide rhythms.

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Cite

BibTeXRIS
BibTeX
@misc{lim2026awake,
  title = {{Awake sharp-wave ripples coincide with rhythmic cortical synchronization}},
  author = {T. H. Lim and X. Zhang},
  howpublished = {bioRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.29.754885},
  url = {https://www.biorxiv.org/content/10.64898/2026.09.29.754885v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - Awake sharp-wave ripples coincide with rhythmic cortical synchronization
AU  - T. H. Lim
AU  - X. Zhang
PY  - 2026
DA  - 2026/09/29
PB  - bioRxiv
DO  - 10.64898/2026.09.29.754885
UR  - https://www.biorxiv.org/content/10.64898/2026.09.29.754885v1
AB  - Analysis of the Allen Institute Visual Coding Neuropixels dataset revealed a ~5 Hz synchronization of visual cortical activity in awake, immobile mice. During bouts of this rhythm, synchronized cortical bursts coincided with changes in the occurrence of sharp-wave ripples (SWRs) and dentate spikes and in SWR properties. Cortical synchronization, SWRs, and dentate spikes were also coordinated with slower pupil-size fluctuation, revealing that awake SWRs are embedded within nested brainwide rhythms.
ER  -