Water as an Active Medium: Distinct Structural-Dynamic Regimes Revealed by Trace Perturbations
- 1TECHNICAL UNIVERSITY OF SOFIA
- 2LUMYCOMP DESIGN LTD
Abstract
Water is commonly treated as a passive solvent in biochemical systems, while temperature-dependent biological activity is often interpreted primarily through kinetic models. In this work, we examine whether enzymatic activity as a function of temperature may reflect not only intrinsic enzyme kinetics, but also a water-dependent structural-dynamic factor. The study compares temperature-response profiles in control water, mechanically activated water, and aqueous systems exposed to trace ionic and structural perturbations. The central question is whether these conditions produce equivalent quantitative shifts or distinct curve signatures, including changes in maximum response temperature, peak width, asymmetry, local curvature, and overall curve class. The analysis suggests that different perturbations may generate non-equivalent temperature profiles, supporting the interpretation of water as an active medium whose structural-dynamic state can influence biochemical behavior. The results are interpreted cautiously as a comparative framework requiring direct replication with locked raw-data acquisition, blinded controls, randomized sample handling, and predefined positive and negative criteria.
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BibTeX
@misc{balevsky2026water,
title = {{Water as an Active Medium: Distinct Structural-Dynamic Regimes Revealed by Trace Perturbations}},
author = {Alexandar Balevsky and Krasimira Ivanova},
howpublished = {Zenodo (CERN European Organization for Nuclear Research)},
year = {2026},
month = jun,
doi = {10.5281/zenodo.20524237},
url = {https://doi.org/10.5281/zenodo.20524237},
note = {CC BY},
}
RIS
TY - UNPB
TI - Water as an Active Medium: Distinct Structural-Dynamic Regimes Revealed by Trace Perturbations
AU - Alexandar Balevsky
AU - Krasimira Ivanova
PY - 2026
DA - 2026/06/03
PB - Zenodo (CERN European Organization for Nuclear Research)
DO - 10.5281/zenodo.20524237
UR - https://doi.org/10.5281/zenodo.20524237
AB - Water is commonly treated as a passive solvent in biochemical systems, while temperature-dependent biological activity is often interpreted primarily through kinetic models. In this work, we examine whether enzymatic activity as a function of temperature may reflect not only intrinsic enzyme kinetics, but also a water-dependent structural-dynamic factor. The study compares temperature-response profiles in control water, mechanically activated water, and aqueous systems exposed to trace ionic and structural perturbations. The central question is whether these conditions produce equivalent quantitative shifts or distinct curve signatures, including changes in maximum response temperature, peak width, asymmetry, local curvature, and overall curve class. The analysis suggests that different perturbations may generate non-equivalent temperature profiles, supporting the interpretation of water as an active medium whose structural-dynamic state can influence biochemical behavior. The results are interpreted cautiously as a comparative framework requiring direct replication with locked raw-data acquisition, blinded controls, randomized sample handling, and predefined positive and negative criteria.
ER -