Ten-Year Reintervention-Free Survival After Surgical Aortic Valve Replacement for Different Prosthetic Aortic Valve Models: Comparison Using Real-World Data From the Netherlands Heart Registration

@article{beaufort2026tenyear,
  title = {{Ten-Year Reintervention-Free Survival After Surgical Aortic Valve Replacement for Different Prosthetic Aortic Valve Models: Comparison Using Real-World Data From the Netherlands Heart Registration}},
  author = {Hector W L de Beaufort and Maaike M Roefs and Edgar J Daeter and Wilson W L Li and Wim Jan P van Boven and Niels P van der Kaaij and Dennis van Veghel and S Bramer and S Bramer and R A F de Lind van Wijngaarden and B M J A Koene and J A Bekkers and G J F Hoohenkerk and A L P Markou and A de Weger and P Segers and D Stecher and R G H Speekenbrink and V G Hindori and W W L Li and E J Daeter and M M Mokhles and I J Wijdh – den Hamer},
  journal = {Interdisciplinary Cardiovascular and Thoracic Surgery},
  year = {2026},
  month = aug,
  doi = {10.1093/icvts/ivag240},
  url = {https://doi.org/10.1093/icvts/ivag240},
  note = {CC BY 4.0},
}

TY  - JOUR
TI  - Ten-Year Reintervention-Free Survival After Surgical Aortic Valve Replacement for Different Prosthetic Aortic Valve Models: Comparison Using Real-World Data From the Netherlands Heart Registration
AU  - Hector W L de Beaufort
AU  - Maaike M Roefs
AU  - Edgar J Daeter
AU  - Wilson W L Li
AU  - Wim Jan P van Boven
AU  - Niels P van der Kaaij
AU  - Dennis van Veghel
AU  - S Bramer
AU  - S Bramer
AU  - R A F de Lind van Wijngaarden
AU  - B M J A Koene
AU  - J A Bekkers
AU  - G J F Hoohenkerk
AU  - A L P Markou
AU  - A de Weger
AU  - P Segers
AU  - D Stecher
AU  - R G H Speekenbrink
AU  - V G Hindori
AU  - W W L Li
AU  - E J Daeter
AU  - M M Mokhles
AU  - I J Wijdh – den Hamer
PY  - 2026
DA  - 2026/08/31
JO  - Interdisciplinary Cardiovascular and Thoracic Surgery
DO  - 10.1093/icvts/ivag240
UR  - https://doi.org/10.1093/icvts/ivag240
AB  - Objectives: To compare long-term outcomes across different models of mechanical and biological aortic valve prostheses after surgical aortic valve replacement (SAVR) in the Netherlands.  Methods: Data from the Netherlands Heart Registration (NHR) on isolated, primary SAVR procedures performed from 2007 to 2018 in adult patients were used, excluding active endocarditis. Ten-year survival and freedom from valve-related reintervention were estimated for models that were implanted >200 times, using Cox proportional hazards models for survival and Fine and Gray’s models with death as the competing event for freedom of reintervention.  Results: For 11 139 patients treated with a biological prosthetic aortic valve, 10-year survival was highest for the Perimount Magna Ease (72.6%) and Epic (70.0%), and significantly lower for the Perimount Magna (65.1%), Trifecta (63.1%), Perimount (61.4%), Freedom Solo (51.5%), and Mitroflow (50.7%). Ten-year freedom from reintervention was highest for the Perimount Magna (99.3%), and significantly lower for the Perimount Magna Ease (98.2%), Perimount (98.2%), Epic (97.3%), Trifecta (96.8%), Freedom Solo (93.2%), and Mitroflow (90.5%). For 2123 patients treated with a mechanical prosthetic aortic valve, 10-year survival was highest for the Regent (91.2%) and not significantly different for the Open Pivot (89.2%), Slimline (87.5%), HP (87.3%), and significantly lower for the Carbomedics Reduced (87.0%). Ten-year freedom from reintervention was highest for the Carbomedics Reduced (97.1%), not significantly different for the Open Pivot (96.1%), Slimline (96.5%), Regent (95.9%), and significantly lower for the HP (94.9%).  Conclusions: Differences in 10-year outcomes after SAVR were observed for the different prosthetic aortic valve models that were used in the NHR, especially for biological prosthetic aortic valve models, with survival varying from 50.7% to 72.6% and freedom from reintervention from 90.5% to 99.3%.
SN  - 2753-670X
ER  -