MOF-on-MOF heterostructured composites for food safety analysis: construction strategies, sensing applications and sample pretreatment.
- 1College of Physical Education, South China Agricultural University Zhujiang College Guangzhou 510900 China.
- 2Shanghai University of Sport Changhai Road 399 Shanghai 200438 China [email protected] [email protected].
Abstract
Food safety requires rapid, sensitive and reliable methods for detecting contaminants in complex food matrices. Metal-organic frameworks (MOFs), owing to their high surface areas, tunable pores and abundant functional sites, have shown considerable potential in food sensing and sample pretreatment. Recently, MOF-on-MOF heterostructures have attracted increasing attention because their hierarchical architectures and tunable interfaces can integrate complementary adsorption, catalytic and signal-transduction functions. This review summarizes the major construction strategies and structural types of MOF-on-MOF materials, with emphasis on epitaxial growth, seed-mediated assembly, interfacial engineering and post-synthetic conversion. Particular attention is given to the distinction between intact MOF-on-MOF heterostructures, MOF-on-MOF-derived materials and related MOF-based hybrids. Recent applications in electrochemical and optical sensing, biosensing-related platforms, and sample pretreatment by magnetic solid-phase extraction (MSPE), solid-phase microextraction (SPME) and dispersive micro-solid-phase extraction (DµSPE) are critically reviewed, together with emerging applications in food preservation and freshness monitoring. Structure-function relationships and analytical performance are discussed beyond sensitivity alone, considering matrix effects, selectivity, reproducibility and stability. Finally, current challenges in mechanistic understanding, material safety, batch-to-batch consistency and scalable fabrication are highlighted. Future priorities include robust real-matrix validation, reproducible synthesis, portable multimodal analysis and more sustainable fabrication, providing guidance for the practical development of MOF-on-MOF materials in food-safety analysis.
Related
- Microwave-Assisted Rapid Synthesis of Cu2S/CoO Heterostructured Composites for High-Performance Asymmetric Supercapacitors
- Lunar Regolith Simulant–Filled High-Performance Thermoplastic Composites for Lunar Construction and Their Potential for Additive Manufacturing
- Optical Stability of Injectable Resin Composites with Different Shade-Matching Strategies
- Processing of PVDF/Nb5+ and Sr2+-Doped PZT Composites for Applications in Advanced Dielectric Insulation: Effect of Ceramic Loading on Structure, Mechanical Properties, Electrical Properties, and Thermal Aging Behavior
- Quantum Computing for Polymeric Composites: Principles, Methods, Applications, and Future Perspectives
BibTeX
@article{chen2026mofonmof,
title = {{MOF-on-MOF heterostructured composites for food safety analysis: construction strategies, sensing applications and sample pretreatment.}},
author = {Zhen Chen and Tingyuan Zheng and Jiahui Cheng and Bing Liu and Zhongquan Li},
journal = {RSC advances},
year = {2026},
month = oct,
doi = {10.1039/d6ra07322k},
url = {https://europepmc.org/article/MED/42851948},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - MOF-on-MOF heterostructured composites for food safety analysis: construction strategies, sensing applications and sample pretreatment.
AU - Zhen Chen
AU - Tingyuan Zheng
AU - Jiahui Cheng
AU - Bing Liu
AU - Zhongquan Li
PY - 2026
DA - 2026/10/08
JO - RSC advances
DO - 10.1039/d6ra07322k
UR - https://europepmc.org/article/MED/42851948
AB - Food safety requires rapid, sensitive and reliable methods for detecting contaminants in complex food matrices. Metal-organic frameworks (MOFs), owing to their high surface areas, tunable pores and abundant functional sites, have shown considerable potential in food sensing and sample pretreatment. Recently, MOF-on-MOF heterostructures have attracted increasing attention because their hierarchical architectures and tunable interfaces can integrate complementary adsorption, catalytic and signal-transduction functions. This review summarizes the major construction strategies and structural types of MOF-on-MOF materials, with emphasis on epitaxial growth, seed-mediated assembly, interfacial engineering and post-synthetic conversion. Particular attention is given to the distinction between intact MOF-on-MOF heterostructures, MOF-on-MOF-derived materials and related MOF-based hybrids. Recent applications in electrochemical and optical sensing, biosensing-related platforms, and sample pretreatment by magnetic solid-phase extraction (MSPE), solid-phase microextraction (SPME) and dispersive micro-solid-phase extraction (DµSPE) are critically reviewed, together with emerging applications in food preservation and freshness monitoring. Structure-function relationships and analytical performance are discussed beyond sensitivity alone, considering matrix effects, selectivity, reproducibility and stability. Finally, current challenges in mechanistic understanding, material safety, batch-to-batch consistency and scalable fabrication are highlighted. Future priorities include robust real-matrix validation, reproducible synthesis, portable multimodal analysis and more sustainable fabrication, providing guidance for the practical development of MOF-on-MOF materials in food-safety analysis.
SN - 2046-2069
ER -