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Peer-reviewedCC BYEpidemiologia (Basel, Switzerland)

Linkage to HIV Care Among Adolescents and Young Adults Reporting a Positive HIV Self-Test in OR Tambo District, Eastern Cape, South Africa.

  1. 1School of Public Health, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha 5100, South Africa.
  2. 2WSU Society and Health Research Institute, Walter Sisulu University, Mthatha 5100, South Africa.

Abstract

Background

HIV self-testing (HIVST) can improve access to HIV testing among adolescents and young adults (AYAs); however, gaps remain in post-test linkage to care. This study examined post-HIVST outcomes and factors associated with reported linkage to HIV care among AYAs in the Eastern Cape, South Africa.Methods

A facility-based cross-sectional study was conducted among 170 AYAs aged 15-24 years who had used HIVST within the preceding five months. Socio-demographic characteristics, HIVST results, post-test care-seeking, and linkage to HIV care were assessed. Bivariate analyses and Firth penalized logistic regression were used to identify factors associated with reported linkage to HIV care among participants reporting a positive HIVST result.Results

Of 156 participants who disclosed their HIVST result, 67 (42.9%) reported a positive result. Among these, 29 (43.3%) sought confirmatory testing, 38 (56.7%) sought care within 1-4 weeks, and 53 (79.1%) reported linkage to HIV care. More than half (55.2%) reported that counselling was not offered, and 59.7% perceived linkage-to-care services as not easily accessible. In multivariable analysis, female participants had higher odds of reporting linkage to HIV care than male participants (AOR = 5.54, 95% CI: 1.49-20.67, p = 0.011).Conclusions

Among AYAs with previous HIVST use, important gaps were observed in confirmatory testing and timely care-seeking. Male AYAs may require targeted support to improve engagement with HIV care services.

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BibTeX
@article{diniso2026linkage,
  title = {{Linkage to HIV Care Among Adolescents and Young Adults Reporting a Positive HIV Self-Test in OR Tambo District, Eastern Cape, South Africa.}},
  author = {Zimkhitha Diniso and Guillermo Alfredo Pulido Estrada and Sibusiso Cyprian Nomatshila and Kululwa Ndayi and Monwabisi Faleni},
  journal = {Epidemiologia (Basel, Switzerland)},
  year = {2026},
  month = oct,
  doi = {10.3390/epidemiologia7050138},
  url = {https://europepmc.org/article/MED/42930326},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Linkage to HIV Care Among Adolescents and Young Adults Reporting a Positive HIV Self-Test in OR Tambo District, Eastern Cape, South Africa.
AU  - Zimkhitha Diniso
AU  - Guillermo Alfredo Pulido Estrada
AU  - Sibusiso Cyprian Nomatshila
AU  - Kululwa Ndayi
AU  - Monwabisi Faleni
PY  - 2026
DA  - 2026/10/07
JO  - Epidemiologia (Basel, Switzerland)
DO  - 10.3390/epidemiologia7050138
UR  - https://europepmc.org/article/MED/42930326
AB  - Background  HIV self-testing (HIVST) can improve access to HIV testing among adolescents and young adults (AYAs); however, gaps remain in post-test linkage to care. This study examined post-HIVST outcomes and factors associated with reported linkage to HIV care among AYAs in the Eastern Cape, South Africa.Methods  A facility-based cross-sectional study was conducted among 170 AYAs aged 15-24 years who had used HIVST within the preceding five months. Socio-demographic characteristics, HIVST results, post-test care-seeking, and linkage to HIV care were assessed. Bivariate analyses and Firth penalized logistic regression were used to identify factors associated with reported linkage to HIV care among participants reporting a positive HIVST result.Results  Of 156 participants who disclosed their HIVST result, 67 (42.9%) reported a positive result. Among these, 29 (43.3%) sought confirmatory testing, 38 (56.7%) sought care within 1-4 weeks, and 53 (79.1%) reported linkage to HIV care. More than half (55.2%) reported that counselling was not offered, and 59.7% perceived linkage-to-care services as not easily accessible. In multivariable analysis, female participants had higher odds of reporting linkage to HIV care than male participants (AOR = 5.54, 95% CI: 1.49-20.67, p = 0.011).Conclusions  Among AYAs with previous HIVST use, important gaps were observed in confirmatory testing and timely care-seeking. Male AYAs may require targeted support to improve engagement with HIV care services.
SN  - 2673-3986
ER  -