Mortality and Epidemiological Characteristics of Pulmonary Embolism in Spain (2022-2024)
- 1Hospital Universitario Severo Ochoa (Madrid, Spain)
Abstract
BackgroundAcute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. This study aims to describe the epidemiological trends, clinical complexity, and in-hospital mortality of PE admissions in Spain from 2022 to 2024.
MethodsWe conducted a nationwide, retrospective study using the Spanish Minimum Basic Data Set for Hospitalization (MBDS-H) for adult patients admitted with acute PE.
ResultsWe identified 125,305 hospital admissions for acute PE. The median patient age was 74 years with a slight male predominance (51-52%). A high comorbidity burden was observed: 61-62% had COPD, 35-37% hypertension, and 21-24% malignancy; ICU admissions increased from 11% to 13% (p < 0.001), with median ICU stay rising from 4 to 7 days (p < 0.001). In-hospital mortality significantly decreased during 2022-2024 from 13.12% to 11.44% (p = 0.013). Mortality per 100,000 inhabitants was consistently higher in men.
ConclusionThis study highlights the high healthcare burden posed by acute embolism in hospitals, demonstrating an increase in patient complexity alongside a decline in overall mortality.
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BibTeX
@misc{mendopedrajas2026mortality,
title = {{Mortality and Epidemiological Characteristics of Pulmonary Embolism in Spain (2022-2024)}},
author = {I. Mendo-Pedrajas and P. Rondon-Fernandez and C. de-Juan-Alvarez and S. Coronado-Fernandez and R. Garcia-Carretero},
howpublished = {medRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.03.26362157},
url = {https://www.medrxiv.org/content/10.64898/2026.09.03.26362157v1},
note = {CC BY-NC-ND},
}
RIS
TY - UNPB
TI - Mortality and Epidemiological Characteristics of Pulmonary Embolism in Spain (2022-2024)
AU - I. Mendo-Pedrajas
AU - P. Rondon-Fernandez
AU - C. de-Juan-Alvarez
AU - S. Coronado-Fernandez
AU - R. Garcia-Carretero
PY - 2026
DA - 2026/09/03
PB - medRxiv
DO - 10.64898/2026.09.03.26362157
UR - https://www.medrxiv.org/content/10.64898/2026.09.03.26362157v1
AB - BackgroundAcute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. This study aims to describe the epidemiological trends, clinical complexity, and in-hospital mortality of PE admissions in Spain from 2022 to 2024. MethodsWe conducted a nationwide, retrospective study using the Spanish Minimum Basic Data Set for Hospitalization (MBDS-H) for adult patients admitted with acute PE. ResultsWe identified 125,305 hospital admissions for acute PE. The median patient age was 74 years with a slight male predominance (51-52%). A high comorbidity burden was observed: 61-62% had COPD, 35-37% hypertension, and 21-24% malignancy; ICU admissions increased from 11% to 13% (p < 0.001), with median ICU stay rising from 4 to 7 days (p < 0.001). In-hospital mortality significantly decreased during 2022-2024 from 13.12% to 11.44% (p = 0.013). Mortality per 100,000 inhabitants was consistently higher in men. ConclusionThis study highlights the high healthcare burden posed by acute embolism in hospitals, demonstrating an increase in patient complexity alongside a decline in overall mortality.
ER -