Skip to content
DraconiticResearch
Search Sources API
185,139 studies31 sourcesUpdated 42 min ago
Peer-reviewedCC BYMolecular therapy. Nucleic acids

Targeted insertion of partial CFTR cDNA replicates native CFTR expression with restored channel function in CF airway epithelium

  • Cristina Barillà1
  • Shingo Suzuki1
  • So Hyun Park2
  • Divyasri Nalluri1
  • Hui Wen3
  • Mohamed A. Hanafy1
  • Daniel Betancourth2
  • Ayushi Umrigar4
  • Shih-Hsing Leir4
  • Katreya Lovrenert4
  • Andrey Sivachenko5
  • Barbara Tabak5
11 more authors
  • Zhong Liu3
  • Rui Zhao3
  • Hillary C. Valley5
  • Andras Rab6
  • Eric J. Sorscher6
  • George M. Solomon1
  • Martin Mense5
  • John P. Carulli5
  • Ann Harris4
  • Gang Bao2
  • Brian R. Davis1
6 affiliations
  1. 1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
  2. 2Department of Bioengineering, Rice University, Houston, TX 77030, USA
  3. 3Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
  4. 4Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH 44106, USA
  5. 5Cystic Fibrosis Foundation Therapeutics Lab, Cystic Fibrosis Foundation, Lexington, MA 02421, USA
  6. 6Department of Pediatrics, School of Medicine, Emory University, Atlanta, GA 30322, USA
Read full textPDFCite

Related

  1. Precision meets scale: DSB- and recombinase-free targeted insertion of large DNA fragments
    Koppolu Raja Rajesh Kumar, Ayushi Singh
    Biodesign researchPeer-reviewedCC BY-NC-NDFull textMolecular biology & gene regulationEurope PMCEurope PMCPMC
  2. Targeted insertion of an optimized donor DNA is effective in a humanized mouse model of dominant retinitis pigmentosa
    Federica Esposito, Arjun Padmanabhan, Manuel Rhiel +14
    Cell Reports MedicinePeer-reviewedCC BY-NC-ND 4.0Full textMolecular biology & gene regulationPMC
  3. New validated reference genes for gene expression studies in the differentiating human airway epithelium
    Joanna Jurczak, Roman Jaksik, Adam Ustaszewski +2
    Scientific ReportsPeer-reviewedCC BY 4.0Full textMolecular biology & gene regulationCrossref
  4. Targeted insertion of partial
    Cristina Barillà, Shingo Suzuki, So Hyun Park +20
    Molecular Therapy: Nucleic AcidsPeer-reviewedCC BYFull textMolecular biology & gene regulationPharmacology & toxicologyDOAJEurope PMCPMC
  5. Promoter-targeted duplex RNAs activate TCF4 expression
    d. corey, B. Janowski, V. Tse +3
    bioRxivPreprintAll rights reservedFull textMolecular biology & gene regulationbioRxiv

Cite

BibTeXRIS
BibTeX
@article{barilla2026targeted,
  title = {{Targeted insertion of partial CFTR cDNA replicates native CFTR expression with restored channel function in CF airway epithelium}},
  author = {Cristina Barillà and Shingo Suzuki and So Hyun Park and Divyasri Nalluri and Hui Wen and Mohamed A. Hanafy and Daniel Betancourth and Ayushi Umrigar and Shih-Hsing Leir and Katreya Lovrenert and Andrey Sivachenko and Barbara Tabak and Zhong Liu and Rui Zhao and Hillary C. Valley and Andras Rab and Eric J. Sorscher and George M. Solomon and Martin Mense and John P. Carulli and Ann Harris and Gang Bao and Brian R. Davis},
  journal = {Molecular therapy. Nucleic acids},
  year = {2026},
  month = oct,
  url = {https://europepmc.org/article/PMC/PMC13717110},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Targeted insertion of partial CFTR cDNA replicates native CFTR expression with restored channel function in CF airway epithelium
AU  - Cristina Barillà
AU  - Shingo Suzuki
AU  - So Hyun Park
AU  - Divyasri Nalluri
AU  - Hui Wen
AU  - Mohamed A. Hanafy
AU  - Daniel Betancourth
AU  - Ayushi Umrigar
AU  - Shih-Hsing Leir
AU  - Katreya Lovrenert
AU  - Andrey Sivachenko
AU  - Barbara Tabak
AU  - Zhong Liu
AU  - Rui Zhao
AU  - Hillary C. Valley
AU  - Andras Rab
AU  - Eric J. Sorscher
AU  - George M. Solomon
AU  - Martin Mense
AU  - John P. Carulli
AU  - Ann Harris
AU  - Gang Bao
AU  - Brian R. Davis
PY  - 2026
DA  - 2026/10/01
JO  - Molecular therapy. Nucleic acids
UR  - https://europepmc.org/article/PMC/PMC13717110
SN  - 2162-2531
ER  -