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Peer-reviewedCC BYBMC Infectious Diseases

Cytomegalovirus enteritis in a patient with AKI after type B aortic dissection surgery: a case report

  • Tongkai Ge1
  • Junqiang Qiu2
  • Zhenzhong Wang2
  • Heng Zuo3
  • Kan Zhou2
  • Changjiang Yu2
  • Huanlei Huang2
  • Tucheng Sun2
  • Yingkai Xiao1
  1. 1Intensive Care Unit, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University
  2. 2Department of Cardiac Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University
  3. 3Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences
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Abstract

Background Cytomegalovirus (CMV) enteritis is an uncommon clinical entity that frequently predisposes to severe complications, such as gastrointestinal (GI) hemorrhage and perforation, and is associated with substantial mortality. Case presentation We herein present the management of a case of CMV enteritis in a patient with “relative immunosuppression”. The patient had a prior history of abdominal aortic replacement and bypass surgery for a type B aortic dissection, following which he developed acute kidney injury (AKI) stage 3 according to KDIGO guidelines. Approximately five weeks after the operation, he presented with massive gastrointestinal hemorrhage and was subsequently diagnosed with CMV enteritis. Treatment included exploratory laparotomy and antiviral therapy with ganciclovir combined with intravenous immunoglobulin, culminating in a successful recovery. Conclusion This case suggests that post-surgical AKI and stress-induced relative immunosuppression may be contributing factors for CMV enteritis in patients without traditional immunocompromise. CT imaging was valuable for early detection of small bowel bleeding in this patient. Prompt surgical intervention may be life-saving for CMV enteritis with life-threatening hemorrhage, providing essential pathological confirmation, while antiviral therapy remains first-line. Clinical trial number Not applicable.

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Cite

BibTeXRIS
BibTeX
@article{ge2026cytomegalovirus,
  title = {{Cytomegalovirus enteritis in a patient with AKI after type B aortic dissection surgery: a case report}},
  author = {Tongkai Ge and Junqiang Qiu and Zhenzhong Wang and Heng Zuo and Kan Zhou and Changjiang Yu and Huanlei Huang and Tucheng Sun and Yingkai Xiao},
  journal = {BMC Infectious Diseases},
  year = {2026},
  month = jul,
  doi = {10.1186/s12879-026-13747-z},
  url = {https://doi.org/10.1186/s12879-026-13747-z},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Cytomegalovirus enteritis in a patient with AKI after type B aortic dissection surgery: a case report
AU  - Tongkai Ge
AU  - Junqiang Qiu
AU  - Zhenzhong Wang
AU  - Heng Zuo
AU  - Kan Zhou
AU  - Changjiang Yu
AU  - Huanlei Huang
AU  - Tucheng Sun
AU  - Yingkai Xiao
PY  - 2026
DA  - 2026/07/01
JO  - BMC Infectious Diseases
DO  - 10.1186/s12879-026-13747-z
UR  - https://doi.org/10.1186/s12879-026-13747-z
AB  - Background Cytomegalovirus (CMV) enteritis is an uncommon clinical entity that frequently predisposes to severe complications, such as gastrointestinal (GI) hemorrhage and perforation, and is associated with substantial mortality. Case presentation We herein present the management of a case of CMV enteritis in a patient with “relative immunosuppression”. The patient had a prior history of abdominal aortic replacement and bypass surgery for a type B aortic dissection, following which he developed acute kidney injury (AKI) stage 3 according to KDIGO guidelines. Approximately five weeks after the operation, he presented with massive gastrointestinal hemorrhage and was subsequently diagnosed with CMV enteritis. Treatment included exploratory laparotomy and antiviral therapy with ganciclovir combined with intravenous immunoglobulin, culminating in a successful recovery. Conclusion This case suggests that post-surgical AKI and stress-induced relative immunosuppression may be contributing factors for CMV enteritis in patients without traditional immunocompromise. CT imaging was valuable for early detection of small bowel bleeding in this patient. Prompt surgical intervention may be life-saving for CMV enteritis with life-threatening hemorrhage, providing essential pathological confirmation, while antiviral therapy remains first-line. Clinical trial number Not applicable.
SN  - 1471-2334
ER  -