Stepwise assembly and mechanical stability of nsP3 Helical Scaffolds in Chikungunya Virus

Abstract

This repository contains the raw HS-AFM datasets and the quantitative data associated with the manuscript. The deposited data are organized as follows: 1. Quantitative dataThe Excel file “Quantitative data.xlsx” contains the quantitative data underlying the graphs presented in the manuscript. 2. Raw HS-AFM moviesThe raw HS-AFM movies are provided in .asd format. These files can be opened and visualized using BioAFMviewer, a freely available software for visualization and analysis of AFM data: https://www.bioafmviewer.com/ 3. AFM–cryo-EM visualization and comparisonTo facilitate the comparison of HS-AFM topographic data with cryo-EM structural data, we developed a custom macro-based workflow, AFM2Chimera_tiff2mrc, which allows AFM TIFF images to be converted into MRC format for visualization in UCSF Chimera. The code is freely available on GitHub: https://github.com/DyNaMo-INSERM/AFM2Chimera_tiff2mrc

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BibTeX RIS

BibTeX

@misc{gonzalez2026stepwise,
  title = {{Stepwise assembly and mechanical stability of nsP3 Helical Scaffolds in Chikungunya Virus}},
  author = {Natalia Martín González and Andrei Karpov and Juan Reguera and Ignacio Casuso},
  howpublished = {HAL},
  year = {2026},
  month = oct,
  doi = {10.5281/zenodo.22231364},
  url = {https://hal.science/hal-05840707v1},
  note = {CC BY-NC 4.0},
}

RIS

TY  - UNPB
TI  - Stepwise assembly and mechanical stability of nsP3 Helical Scaffolds in Chikungunya Virus
AU  - Natalia Martín González
AU  - Andrei Karpov
AU  - Juan Reguera
AU  - Ignacio Casuso
PY  - 2026
DA  - 2026/10/27
PB  - HAL
DO  - 10.5281/zenodo.22231364
UR  - https://hal.science/hal-05840707v1
AB  - This repository contains the raw HS-AFM datasets and the quantitative data associated with the manuscript. The deposited data are organized as follows: 1. Quantitative dataThe Excel file “Quantitative data.xlsx” contains the quantitative data underlying the graphs presented in the manuscript. 2. Raw HS-AFM moviesThe raw HS-AFM movies are provided in .asd format. These files can be opened and visualized using BioAFMviewer, a freely available software for visualization and analysis of AFM data: https://www.bioafmviewer.com/ 3. AFM–cryo-EM visualization and comparisonTo facilitate the comparison of HS-AFM topographic data with cryo-EM structural data, we developed a custom macro-based workflow, AFM2Chimera_tiff2mrc, which allows AFM TIFF images to be converted into MRC format for visualization in UCSF Chimera. The code is freely available on GitHub: https://github.com/DyNaMo-INSERM/AFM2Chimera_tiff2mrc
ER  -

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