En bloc multivisceral resection for a giant retroperitoneal dedifferentiated liposarcoma: technical considerations.
- 1Department of General Surgery, The Dudley Group NHS Foundation Trust, Pensnett Road, Dudley, West Midlands, DY1 2HQ, United Kingdom.
- 2College of Health and Life Science, Aston Medical School, School of Medicine, Pharmacy and Biosciences, Aston University, Birmingham B4 7ET, UK, United Kingdom.
- 3Department of Gastrointestinal Surgery AST Ascoli Piceno, Madonna del Soccorso Hospital, San Benedetto del Tronto, Italy.
Abstract
Retroperitoneal sarcomas are rare, aggressive malignancies that often present late owing to the retroperitoneum's anatomical expansibility. Dedifferentiated liposarcoma is the most common high-grade subtype. We describe the technical management of a 65-year-old man with a giant retroperitoneal dedifferentiated liposarcoma involving multiple adjacent organs, treated by radical en bloc multivisceral resection including the kidney, adrenal gland, spleen, and distal pancreas. Postoperative recovery was complicated by a Grade B pancreatic leak and a left pleural effusion, managed with percutaneous and thoracic drainage, respectively. Histology confirmed a dedifferentiated liposarcoma resected with clear (R0) margins. At 18 months, no radiological recurrence had been observed, although this follow-up interval remains short relative to the recurrence interval reported for high-grade dedifferentiated liposarcoma. This case illustrates the technical conduct of multivisceral resection for a giant retroperitoneal sarcoma and the perioperative surveillance required to manage expected complications such as pancreatic leak.
Related
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BibTeX
@article{alhassani2026bloc,
title = {{En bloc multivisceral resection for a giant retroperitoneal dedifferentiated liposarcoma: technical considerations.}},
author = {Sadik Al-Hassani and Akinfemi Akingboye and Ilenia Merlini and Salomone Di Saverio},
journal = {Journal of surgical case reports},
year = {2026},
month = oct,
doi = {10.1093/jscr/rjag982},
url = {https://europepmc.org/article/MED/42948301},
note = {CC BY},
}
RIS
TY - JOUR
TI - En bloc multivisceral resection for a giant retroperitoneal dedifferentiated liposarcoma: technical considerations.
AU - Sadik Al-Hassani
AU - Akinfemi Akingboye
AU - Ilenia Merlini
AU - Salomone Di Saverio
PY - 2026
DA - 2026/10/27
JO - Journal of surgical case reports
DO - 10.1093/jscr/rjag982
UR - https://europepmc.org/article/MED/42948301
AB - Retroperitoneal sarcomas are rare, aggressive malignancies that often present late owing to the retroperitoneum's anatomical expansibility. Dedifferentiated liposarcoma is the most common high-grade subtype. We describe the technical management of a 65-year-old man with a giant retroperitoneal dedifferentiated liposarcoma involving multiple adjacent organs, treated by radical en bloc multivisceral resection including the kidney, adrenal gland, spleen, and distal pancreas. Postoperative recovery was complicated by a Grade B pancreatic leak and a left pleural effusion, managed with percutaneous and thoracic drainage, respectively. Histology confirmed a dedifferentiated liposarcoma resected with clear (R0) margins. At 18 months, no radiological recurrence had been observed, although this follow-up interval remains short relative to the recurrence interval reported for high-grade dedifferentiated liposarcoma. This case illustrates the technical conduct of multivisceral resection for a giant retroperitoneal sarcoma and the perioperative surveillance required to manage expected complications such as pancreatic leak.
SN - 2042-8812
ER -