Case Report: transient migratory pulmonary nodules with bronchial artery malformations in an autosomal dominant polycystic kidney disease patient: a case of recurrent hemoptysis.
- 1Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated with Tsinghua University, Beijing, China.
Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is associated with vascular malformations, but bronchial artery involvement with migratory pulmonary nodules has not been reported. We describe an 81-year-old man with recurrent hemoptysis and migratory nodules on chest CT. Digital subtraction angiography revealed tortuous, dilated bronchial arteries; embolization controlled bleeding and nodules resolved. He had polycystic kidney and liver disease, a prior intracranial aneurysm, and a PKD1 missense variant (c.8426C > T). Common causes of hemoptysis were excluded. This case describes co-occurrence of bronchial artery malformation, recurrent hemoptysis and migratory pulmonary nodules in a patient with genetically confirmed ADPKD, raising the possibility that bronchial arterial involvement could be a rare, under-recognized vascular manifestation associated with ADPKD.
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BibTeX
@article{hu2026case,
title = {{Case Report: transient migratory pulmonary nodules with bronchial artery malformations in an autosomal dominant polycystic kidney disease patient: a case of recurrent hemoptysis.}},
author = {Yi Hu and Jie Zhang and Ting Wang and Bing Xue},
journal = {Frontiers in medicine},
year = {2026},
month = oct,
doi = {10.3389/fmed.2026.1949035},
url = {https://europepmc.org/article/MED/42953645},
note = {CC BY},
}
RIS
TY - JOUR
TI - Case Report: transient migratory pulmonary nodules with bronchial artery malformations in an autosomal dominant polycystic kidney disease patient: a case of recurrent hemoptysis.
AU - Yi Hu
AU - Jie Zhang
AU - Ting Wang
AU - Bing Xue
PY - 2026
DA - 2026/10/14
JO - Frontiers in medicine
DO - 10.3389/fmed.2026.1949035
UR - https://europepmc.org/article/MED/42953645
AB - Autosomal dominant polycystic kidney disease (ADPKD) is associated with vascular malformations, but bronchial artery involvement with migratory pulmonary nodules has not been reported. We describe an 81-year-old man with recurrent hemoptysis and migratory nodules on chest CT. Digital subtraction angiography revealed tortuous, dilated bronchial arteries; embolization controlled bleeding and nodules resolved. He had polycystic kidney and liver disease, a prior intracranial aneurysm, and a PKD1 missense variant (c.8426C > T). Common causes of hemoptysis were excluded. This case describes co-occurrence of bronchial artery malformation, recurrent hemoptysis and migratory pulmonary nodules in a patient with genetically confirmed ADPKD, raising the possibility that bronchial arterial involvement could be a rare, under-recognized vascular manifestation associated with ADPKD.
SN - 2296-858X
ER -