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Peer-reviewedCC BY-NC 4.0Case Reports in Ophthalmology

Iridocorneal Endothelial Syndrome after Implantation Collamer Lens: A Case Report

  1. 1Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China
  2. 2National Health Commission Key Lab of Myopia (Fudan University), Shanghai, China
  3. 3Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China

Abstract

Introduction: We describe a case of iridocorneal endothelial (ICE) syndrome 13 years after a bilateral insertion of implantable Collamer lenses in a patient to rectify severe myopia.

Case Presentation: A 31-year-old woman presented to our hospital with elevated intraocular pressure detected during a routine physical examination. She had undergone bilateral implantable Collamer lens implantation 13 years ago to correct her high myopia. Slit lamp examination revealed appropriate vaulting of the lenses in both eyes. The right eye was structurally normal, but the left eye showed peripheral corneal opacity and edema, slight pigmented keratic precipitates, pupil displacement, sluggish response to light, iris atrophy, and peripheral anterior iris adhesions. In vivo confocal microscopy demonstrated enlargement of the endothelial cells in the left eye, with hyper-reflective nuclei of diverse shapes and visible mitotic images. The diagnosis was ICE syndrome.

Conclusion: Our report is the first to document the occurrence of ICE syndrome in pseudophakic eyes, with no preoperative abnormalities noted.

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BibTeX
@article{luo2026iridocorneal,
  title = {{Iridocorneal Endothelial Syndrome after Implantation Collamer Lens: A Case Report}},
  author = {Xiumei Luo and Yishan Qian and Xiaoying Wang},
  journal = {Case Reports in Ophthalmology},
  year = {2026},
  month = sep,
  doi = {10.1159/cop/acaag017},
  url = {https://doi.org/10.1159/cop/acaag017},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - Iridocorneal Endothelial Syndrome after Implantation Collamer Lens: A Case Report
AU  - Xiumei Luo
AU  - Yishan Qian
AU  - Xiaoying Wang
PY  - 2026
DA  - 2026/09/24
JO  - Case Reports in Ophthalmology
DO  - 10.1159/cop/acaag017
UR  - https://doi.org/10.1159/cop/acaag017
AB  - Introduction: We describe a case of iridocorneal endothelial (ICE) syndrome 13 years after a bilateral insertion of implantable Collamer lenses in a patient to rectify severe myopia.  Case Presentation: A 31-year-old woman presented to our hospital with elevated intraocular pressure detected during a routine physical examination. She had undergone bilateral implantable Collamer lens implantation 13 years ago to correct her high myopia. Slit lamp examination revealed appropriate vaulting of the lenses in both eyes. The right eye was structurally normal, but the left eye showed peripheral corneal opacity and edema, slight pigmented keratic precipitates, pupil displacement, sluggish response to light, iris atrophy, and peripheral anterior iris adhesions. In vivo confocal microscopy demonstrated enlargement of the endothelial cells in the left eye, with hyper-reflective nuclei of diverse shapes and visible mitotic images. The diagnosis was ICE syndrome.  Conclusion: Our report is the first to document the occurrence of ICE syndrome in pseudophakic eyes, with no preoperative abnormalities noted.
SN  - 1663-2699
ER  -