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Peer-reviewedCC BY-NCClinical interventions in aging

The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.

  1. 1Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, Iran.
  2. 2Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, Iran.
  3. 3Isfahan University of Medical Sciences, Department of Orthopedics and Joint Surgery, Isfahan, Iran.

Abstract

Purpose

To determine the effect of mindfulness-based cognitive therapy on kinesiophobia in older adults with chronic knee osteoarthritis.Patients and methods

This randomized clinical trial conducted among 56 older patients with knee osteoarthritis at health centers in Kashan, Iran, in 2024. Participants were selected via consecutive sampling and randomly assigned to either an intervention (n = 28) or a control (n = 28) group using block randomization. The intervention group participated in eight 90 minute sessions of Mindfulness Based Cognitive Therapy, while the control group received routine care. Kinesiophobia was measured with the Tampa Scale for Kinesiophobia (TSK11) at baseline, week 4 (immediately post intervention), and week 8 (four week follow up). Covariate adjusted repeated measures ANCOVA was performed, adjusting for age, number of children, and baseline pain intensity. Statistical significance was set at p < 0.05. All participants completed follow up.Results

The mean kinesiophobia score decreased from 29.46 ± 3.81 at baseline to 25.68 ± 3.22 at week 8 in the intervention group and from 28.64 ± 4.78 to 26.68 ± 5.15 in the control group. The adjusted repeated-measures analysis showed a significant group-by-time interaction (Wilks' Λ = 0.88, F(2.50) = 3.34, p = 0.040, ηp² = 0.11), indicating different trajectories of change between groups. However, adjusted between-group differences were not statistically significant at baseline, week 4, or week 8 (all p > 0.05). The adjusted difference in change from baseline to week 8 was -1.60 points (95% CI -3.25 to 0.05; p = 0.05). Within-group Bonferroni-adjusted comparisons showed significant reductions across all time intervals in the intervention group (all p < 0.001) and from baseline to week 4 and week 8 in the control group (p = 0.0022 and p = 0.0028, respectively), but not between weeks 4 and 8 (p = 0.13).Conclusion

Four weeks of MBCT may influence the trajectory of kinesiophobia over time in older adults with knee osteoarthritis.Trial registration

Registered in the Iranian Registry of Clinical Trials (IRCT20231105059961N1).

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BibTeX
@article{kheirkhah2026effect,
  title = {{The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.}},
  author = {Zahra Kheirkhah and Fatemeh Fallahi and Khadijeh Sharifi and Fatemeh Sadat Asgarian and Amir Hossein Fallahi},
  journal = {Clinical interventions in aging},
  year = {2026},
  month = oct,
  doi = {10.2147/cia.s638393},
  url = {https://europepmc.org/article/MED/42927343},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.
AU  - Zahra Kheirkhah
AU  - Fatemeh Fallahi
AU  - Khadijeh Sharifi
AU  - Fatemeh Sadat Asgarian
AU  - Amir Hossein Fallahi
PY  - 2026
DA  - 2026/10/20
JO  - Clinical interventions in aging
DO  - 10.2147/cia.s638393
UR  - https://europepmc.org/article/MED/42927343
AB  - Purpose  To determine the effect of mindfulness-based cognitive therapy on kinesiophobia in older adults with chronic knee osteoarthritis.Patients and methods  This randomized clinical trial conducted among 56 older patients with knee osteoarthritis at health centers in Kashan, Iran, in 2024. Participants were selected via consecutive sampling and randomly assigned to either an intervention (n = 28) or a control (n = 28) group using block randomization. The intervention group participated in eight 90 minute sessions of Mindfulness Based Cognitive Therapy, while the control group received routine care. Kinesiophobia was measured with the Tampa Scale for Kinesiophobia (TSK11) at baseline, week 4 (immediately post intervention), and week 8 (four week follow up). Covariate adjusted repeated measures ANCOVA was performed, adjusting for age, number of children, and baseline pain intensity. Statistical significance was set at p < 0.05. All participants completed follow up.Results  The mean kinesiophobia score decreased from 29.46 ± 3.81 at baseline to 25.68 ± 3.22 at week 8 in the intervention group and from 28.64 ± 4.78 to 26.68 ± 5.15 in the control group. The adjusted repeated-measures analysis showed a significant group-by-time interaction (Wilks' Λ = 0.88, F(2.50) = 3.34, p = 0.040, ηp² = 0.11), indicating different trajectories of change between groups. However, adjusted between-group differences were not statistically significant at baseline, week 4, or week 8 (all p > 0.05). The adjusted difference in change from baseline to week 8 was -1.60 points (95% CI -3.25 to 0.05; p = 0.05). Within-group Bonferroni-adjusted comparisons showed significant reductions across all time intervals in the intervention group (all p < 0.001) and from baseline to week 4 and week 8 in the control group (p = 0.0022 and p = 0.0028, respectively), but not between weeks 4 and 8 (p = 0.13).Conclusion  Four weeks of MBCT may influence the trajectory of kinesiophobia over time in older adults with knee osteoarthritis.Trial registration  Registered in the Iranian Registry of Clinical Trials (IRCT20231105059961N1).
SN  - 1176-9092
SN  - 1178-1998
ER  -