Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study

@article{mitri2026direct,
  title = {{Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study}},
  author = {Elise Mitri and Sara Vogrin and Camille Paynter and Luke Fletcher and Jonny Peter and Neil Powell and Sara Barnes and Philip Li and Ana Maria Copaescu and Nicholas Turner and Fiona James and Richard Sullivan and Maryam Sherkat Masoum and Matthew Rawlins and Geoff Mackay and Benjamin Smith and Patricia Kilfoyle and Daniel Forster and Morgan Rose and Raquel Cowan and Kylie Alcorn and Anna Brischetto and Andrew Mahony and Andrew Redmond and Arindam Chakravorty and Zaal Meher-Homji and Chino Yuson and Simeon Crawford and Greg Weeks and Sasheela Sri La Sri Ponnampalavanar and Constance Katelaris and Priscilla Tran and Jennifer O'Hern and Jack Godsell and Trisha Peel and Indy Sandaradura and David New and Candice Holland and Tim Cutfield and Sarah Coghill and Caitlin Hand and Jacob Williams and Jaclyn Bishop and Belinda Lambros and Cascia Day and Courtney Ierano and Natasha Holmes and Jason A. Roberts and Suran Fernando and Marlena Klaic and Jason Trubiano and Jennifer O’hern and Kyra Chua and Joseph de Luca and Gemma Reynolds and Evelyn Andrews and Daniel Lapirow and Abby Douglas and Tanya Crichton and Kate Guy},
  journal = {Clinical Infectious Diseases},
  year = {2026},
  month = jun,
  doi = {10.1093/cid/ciag083},
  url = {https://hal.science/hal-05834910v1},
  note = {CC BY-NC-ND 4.0},
}

TY  - JOUR
TI  - Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study
AU  - Elise Mitri
AU  - Sara Vogrin
AU  - Camille Paynter
AU  - Luke Fletcher
AU  - Jonny Peter
AU  - Neil Powell
AU  - Sara Barnes
AU  - Philip Li
AU  - Ana Maria Copaescu
AU  - Nicholas Turner
AU  - Fiona James
AU  - Richard Sullivan
AU  - Maryam Sherkat Masoum
AU  - Matthew Rawlins
AU  - Geoff Mackay
AU  - Benjamin Smith
AU  - Patricia Kilfoyle
AU  - Daniel Forster
AU  - Morgan Rose
AU  - Raquel Cowan
AU  - Kylie Alcorn
AU  - Anna Brischetto
AU  - Andrew Mahony
AU  - Andrew Redmond
AU  - Arindam Chakravorty
AU  - Zaal Meher-Homji
AU  - Chino Yuson
AU  - Simeon Crawford
AU  - Greg Weeks
AU  - Sasheela Sri La Sri Ponnampalavanar
AU  - Constance Katelaris
AU  - Priscilla Tran
AU  - Jennifer O'Hern
AU  - Jack Godsell
AU  - Trisha Peel
AU  - Indy Sandaradura
AU  - David New
AU  - Candice Holland
AU  - Tim Cutfield
AU  - Sarah Coghill
AU  - Caitlin Hand
AU  - Jacob Williams
AU  - Jaclyn Bishop
AU  - Belinda Lambros
AU  - Cascia Day
AU  - Courtney Ierano
AU  - Natasha Holmes
AU  - Jason A. Roberts
AU  - Suran Fernando
AU  - Marlena Klaic
AU  - Jason Trubiano
AU  - Jennifer O’hern
AU  - Kyra Chua
AU  - Joseph de Luca
AU  - Gemma Reynolds
AU  - Evelyn Andrews
AU  - Daniel Lapirow
AU  - Abby Douglas
AU  - Tanya Crichton
AU  - Kate Guy
PY  - 2026
DA  - 2026/06/15
JO  - Clinical Infectious Diseases
DO  - 10.1093/cid/ciag083
UR  - https://hal.science/hal-05834910v1
AB  - In this international, multicenter prospective study, implementing penicillin direct oral challenge (DOC) using a digital toolkit was acceptable, feasible, and sustainable. Audit and feedback increased activity, particularly among pharmacists. Safety was maintained across heterogeneous DOC protocols, validating a pragmatic, scalable approach that supports local adaptation.
SN  - 1058-4838
SN  - 1537-6591
ER  -