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PreprintCC BYmedRxiv

When the forest speaks again: in-depth genomic analysis of serotyping failure reveals geographic extension of sylvatic DENV-2 in southeastern Senegal, 2026

  • I. DIENG1
  • A. S. Efire
  • S. N. Sagne
  • M. H. D. Ndione
  • D. Camara
  • S. F. M. Doukanda
  • N. Dia
  • B. Diallo
  • M. A. Barry
  • G. Fall
  • O. Fall
  1. 1Institut pasteur de Dakar
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Abstract

In August 2026, eight febrile patients in the Kedougou and Tambacounda regions of Senegal tested positive by pan-flavivirus and pan-dengue RT-PCR but could not be assigned to a serotype. In-depth genome sequencing identified sylvatic dengue virus serotype 2 (DENV-2, genotype VI). These findings indicate the re-emergence and geographic spread of DENV-2/GVI beyond its historical focus.

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Cite

BibTeXRIS
BibTeX
@misc{dieng2026when,
  title = {{When the forest speaks again: in-depth genomic analysis of serotyping failure reveals geographic extension of sylvatic DENV-2 in southeastern Senegal, 2026}},
  author = {I. DIENG and A. S. Efire and S. N. Sagne and M. H. D. Ndione and D. Camara and S. F. M. Doukanda and N. Dia and B. Diallo and M. A. Barry and G. Fall and O. Fall},
  howpublished = {medRxiv},
  year = {2026},
  month = oct,
  doi = {10.64898/2026.10.19.26365950},
  url = {https://www.medrxiv.org/content/10.64898/2026.10.19.26365950v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - When the forest speaks again: in-depth genomic analysis of serotyping failure reveals geographic extension of sylvatic DENV-2 in southeastern Senegal, 2026
AU  - I. DIENG
AU  - A. S. Efire
AU  - S. N. Sagne
AU  - M. H. D. Ndione
AU  - D. Camara
AU  - S. F. M. Doukanda
AU  - N. Dia
AU  - B. Diallo
AU  - M. A. Barry
AU  - G. Fall
AU  - O. Fall
PY  - 2026
DA  - 2026/10/19
PB  - medRxiv
DO  - 10.64898/2026.10.19.26365950
UR  - https://www.medrxiv.org/content/10.64898/2026.10.19.26365950v1
AB  - In August 2026, eight febrile patients in the Kedougou and Tambacounda regions of Senegal tested positive by pan-flavivirus and pan-dengue RT-PCR but could not be assigned to a serotype. In-depth genome sequencing identified sylvatic dengue virus serotype 2 (DENV-2, genotype VI). These findings indicate the re-emergence and geographic spread of DENV-2/GVI beyond its historical focus.
ER  -