Uncontrolled metabolic syndrome associated with poorer sleep quality in adults in rural areas: a secondary analysis.
4 affiliations
- 1Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
- 2Department of Population Health, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
- 3Department of Physical Therapy, Rehabilitation Science, and Athletic Training, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
- 4Department of Dietetics and Nutrition, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Abstract
To examine whether clinical management of metabolic syndrome (MetS) is associated with sleep health among adults receiving care in rural primary care settings. This cross-sectional analysis used baseline data from adults (age 20-75 years; body mass index (BMI) 30-45 kg/m2) enrolled in the RE-POWER trial, a pragmatic behavioral weight loss intervention implemented in rural primary care clinics. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). MetS was defined according to American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) criteria and categorized as: (1) no-MetS, (2) controlled MetS (criteria met via medication use), and (3) uncontrolled MetS (criteria met via abnormal laboratory values). Linear mixed models evaluated whether MetS status predicted global PSQI, PSQI subcomponents, and sleep duration, adjusting for age, sex, and BMI. Among 1406 adults (mean age 54.6 ± 11.8 years; 76.8% female), those with uncontrolled MetS (n = 634) had significantly worse global PSQI, sleep latency, and sleep disturbance scores compared with adults without MetS (n = 483) (P < .05). Sleep outcomes did not differ between adults with controlled MetS (n = 289) and those without MetS (P > .05). Poorly controlled MetS was associated with poorer sleep quality, whereas clinically controlled MetS was not. Future research is needed to determine if effective clinical management of MetS may confer benefits for sleep health in rural populations.
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BibTeX
@article{hastert2026uncontrolled,
title = {{Uncontrolled metabolic syndrome associated with poorer sleep quality in adults in rural areas: a secondary analysis.}},
author = {Mary C Hastert and Danny Kurz and Catherine Siengsukon and Debra K Sullivan and Christie Befort},
journal = {Journal of the Endocrine Society},
year = {2026},
month = oct,
doi = {10.1210/jendso/bvag251},
url = {https://europepmc.org/article/MED/42996849},
note = {CC BY},
}
RIS
TY - JOUR
TI - Uncontrolled metabolic syndrome associated with poorer sleep quality in adults in rural areas: a secondary analysis.
AU - Mary C Hastert
AU - Danny Kurz
AU - Catherine Siengsukon
AU - Debra K Sullivan
AU - Christie Befort
PY - 2026
DA - 2026/10/28
JO - Journal of the Endocrine Society
DO - 10.1210/jendso/bvag251
UR - https://europepmc.org/article/MED/42996849
AB - To examine whether clinical management of metabolic syndrome (MetS) is associated with sleep health among adults receiving care in rural primary care settings. This cross-sectional analysis used baseline data from adults (age 20-75 years; body mass index (BMI) 30-45 kg/m2) enrolled in the RE-POWER trial, a pragmatic behavioral weight loss intervention implemented in rural primary care clinics. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). MetS was defined according to American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) criteria and categorized as: (1) no-MetS, (2) controlled MetS (criteria met via medication use), and (3) uncontrolled MetS (criteria met via abnormal laboratory values). Linear mixed models evaluated whether MetS status predicted global PSQI, PSQI subcomponents, and sleep duration, adjusting for age, sex, and BMI. Among 1406 adults (mean age 54.6 ± 11.8 years; 76.8% female), those with uncontrolled MetS (n = 634) had significantly worse global PSQI, sleep latency, and sleep disturbance scores compared with adults without MetS (n = 483) (P < .05). Sleep outcomes did not differ between adults with controlled MetS (n = 289) and those without MetS (P > .05). Poorly controlled MetS was associated with poorer sleep quality, whereas clinically controlled MetS was not. Future research is needed to determine if effective clinical management of MetS may confer benefits for sleep health in rural populations.
SN - 2472-1972
ER -