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Peer-reviewedCC BYFrontiers in surgery

Case Report: Solitary fibrous tumor (SFT) of cerebellum: report of 2 cases.

  • Gaochao Guo1
  • Zongzong Ma2
  • Liming Zhao1
  • Tao Gao1
  • Yuxue Sun1
  • Ziqiang Liu1
  • Yang Liu1
  • Chaoyue Li1
  1. 1Department of Neurosurgery, Henan Provincial People's Hospital, Zhengzhou, China.
  2. 2Department of Neurosurgery, Nanyang Nanshi Hospital, Nanyang, China.
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Abstract

To elucidate the neuroradiological characteristics, clinical manifestations, and surgical outcomes of intracranial cerebellar solitary fibrous tumors (SFTs) to improve diagnostic accuracy and therapeutic strategies. A retrospective analysis was conducted on the clinical data of two histopathologically confirmed cases of cerebellar SFT, supplemented by a review of the relevant literature. Both patients underwent total surgical excision followed by postoperative radiotherapy. At the latest follow-up, neither patient showed radiological evidence of tumor recurrence (Case 1: 18 months; Case 2: 12 months]). Given the potential for late recurrence in SFTs, long-term surveillance is mandatory. Intracranial cerebellar SFTs are rare neoplasms that are frequently misdiagnosed despite exhibiting distinctive magnetic resonance imaging (MRI) features. Definitive diagnosis relies on histopathological and immunohistochemical analyses. In this study, MRI demonstrated T1-weighted imaging (T1WI) hypointensity or isointensity, T2-weighted imaging (T2WI) heterogeneity, and inconsistent post-contrast enhancement. Immunohistochemical evaluation revealed positivity for CD34, CD99, and STAT6. Prompt surgical intervention accompanied by adjuvant therapy was associated with a favorable prognosis.

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Cite

BibTeXRIS
BibTeX
@article{guo2026case,
  title = {{Case Report: Solitary fibrous tumor (SFT) of cerebellum: report of 2 cases.}},
  author = {Gaochao Guo and Zongzong Ma and Liming Zhao and Tao Gao and Yuxue Sun and Ziqiang Liu and Yang Liu and Chaoyue Li},
  journal = {Frontiers in surgery},
  year = {2026},
  month = oct,
  doi = {10.3389/fsurg.2026.1944873},
  url = {https://europepmc.org/article/MED/42953671},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Case Report: Solitary fibrous tumor (SFT) of cerebellum: report of 2 cases.
AU  - Gaochao Guo
AU  - Zongzong Ma
AU  - Liming Zhao
AU  - Tao Gao
AU  - Yuxue Sun
AU  - Ziqiang Liu
AU  - Yang Liu
AU  - Chaoyue Li
PY  - 2026
DA  - 2026/10/14
JO  - Frontiers in surgery
DO  - 10.3389/fsurg.2026.1944873
UR  - https://europepmc.org/article/MED/42953671
AB  - To elucidate the neuroradiological characteristics, clinical manifestations, and surgical outcomes of intracranial cerebellar solitary fibrous tumors (SFTs) to improve diagnostic accuracy and therapeutic strategies. A retrospective analysis was conducted on the clinical data of two histopathologically confirmed cases of cerebellar SFT, supplemented by a review of the relevant literature. Both patients underwent total surgical excision followed by postoperative radiotherapy. At the latest follow-up, neither patient showed radiological evidence of tumor recurrence (Case 1: 18 months; Case 2: 12 months]). Given the potential for late recurrence in SFTs, long-term surveillance is mandatory. Intracranial cerebellar SFTs are rare neoplasms that are frequently misdiagnosed despite exhibiting distinctive magnetic resonance imaging (MRI) features. Definitive diagnosis relies on histopathological and immunohistochemical analyses. In this study, MRI demonstrated T1-weighted imaging (T1WI) hypointensity or isointensity, T2-weighted imaging (T2WI) heterogeneity, and inconsistent post-contrast enhancement. Immunohistochemical evaluation revealed positivity for CD34, CD99, and STAT6. Prompt surgical intervention accompanied by adjuvant therapy was associated with a favorable prognosis.
SN  - 2296-875X
ER  -