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Peer-reviewedCC BY 4.0Cell Reports Physical Science

Stratum corneum lipids in a hydration gradient exhibit robust lamellar organization and responsive fluidity

Abstract

In briefLabecka et al. show that increasing hydration enhances lipid fluidity at the molecular scale while leaving the mesoscopic lamellar structure unchanged in stratum corneum lipids. Under hydration gradients, oriented multilayers form and provide a platform to probe molecular transport across the skin barrier.

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BibTeX
@article{labecka2026stratum,
  title = {{Stratum corneum lipids in a hydration gradient exhibit robust lamellar organization and responsive fluidity}},
  author = {Nikol Labecka and Enamul H Mojumdar and Jenny M Andersson and Nicolas Velasquez and Yoshihiko Sonoki and Kim Nygård and Mads Carlsen and Kevin Roger and Emma Sparr},
  journal = {Cell Reports Physical Science},
  year = {2026},
  month = jul,
  doi = {10.1016/j.xcrp.2026.103381},
  url = {https://hal.science/hal-05848133v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Stratum corneum lipids in a hydration gradient exhibit robust lamellar organization and responsive fluidity
AU  - Nikol Labecka
AU  - Enamul H Mojumdar
AU  - Jenny M Andersson
AU  - Nicolas Velasquez
AU  - Yoshihiko Sonoki
AU  - Kim Nygård
AU  - Mads Carlsen
AU  - Kevin Roger
AU  - Emma Sparr
PY  - 2026
DA  - 2026/07/15
JO  - Cell Reports Physical Science
DO  - 10.1016/j.xcrp.2026.103381
UR  - https://hal.science/hal-05848133v1
AB  - In briefLabecka et al. show that increasing hydration enhances lipid fluidity at the molecular scale while leaving the mesoscopic lamellar structure unchanged in stratum corneum lipids. Under hydration gradients, oriented multilayers form and provide a platform to probe molecular transport across the skin barrier.
SN  - 2666-3864
ER  -