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Peer-reviewedCC BY-NCArchives of academic emergency medicine

Myocardial Infarction with Non-obstructive Coronary Arteries; Diffuse Large B-Cell Lymphoma Presenting as an Acute Coronary Syndrome.

  1. 1Department of Emergency Medicine, Gold Coast Hospital and Health Service, Queensland, Australia.
  2. 2Department of Cardiology, Gold Coast Hospital and Health Service, Queensland, Australia.
  3. 3Department of Haematology, Gold Coast Hospital and Health Service, Queensland, Australia.

Abstract

A 69-year-old man presented with sudden-onset crushing chest pain, diaphoresis, and syncope with ECG findings prompting treatment as a ST-elevation myocardial infarction (STEMI). Emergency coronary angiography demonstrated no obstructive coronary artery disease. Subsequent investigations including cardiac magnetic resonance imaging (MRI) and positron emission tomography (PET) scan demonstrated an infiltrative mass. Biopsy of a supraclavicular lymph node established a diagnosis of diffuse large B-cell lymphoma (DLBCL) with cardiac involvement. The patient was treated with corticosteroids and immunochemotherapy (DA-R-EPOCH), achieving complete remission on surveillance imaging. This case therefore contributes valuable evidence regarding the varied cardiovascular manifestations of lymphoma and reinforces the importance of maintaining a broad differential diagnosis in patients presenting with features of myocardial infarction with non-obstructive coronary arteries (MINOCA).

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BibTeX
@article{deshpande2026myocardial,
  title = {{Myocardial Infarction with Non-obstructive Coronary Arteries; Diffuse Large B-Cell Lymphoma Presenting as an Acute Coronary Syndrome.}},
  author = {Rahul Vilas Deshpande and Gregory Milne Aroney and Teng Fong Ng and Erin Jayne Stirling and Alireza Baratloo},
  journal = {Archives of academic emergency medicine},
  year = {2026},
  month = sep,
  doi = {10.22037/aaem.v14i1.3130},
  url = {https://europepmc.org/article/MED/42936799},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Myocardial Infarction with Non-obstructive Coronary Arteries; Diffuse Large B-Cell Lymphoma Presenting as an Acute Coronary Syndrome.
AU  - Rahul Vilas Deshpande
AU  - Gregory Milne Aroney
AU  - Teng Fong Ng
AU  - Erin Jayne Stirling
AU  - Alireza Baratloo
PY  - 2026
DA  - 2026/09/10
JO  - Archives of academic emergency medicine
DO  - 10.22037/aaem.v14i1.3130
UR  - https://europepmc.org/article/MED/42936799
AB  - A 69-year-old man presented with sudden-onset crushing chest pain, diaphoresis, and syncope with ECG findings prompting treatment as a ST-elevation myocardial infarction (STEMI). Emergency coronary angiography demonstrated no obstructive coronary artery disease. Subsequent investigations including cardiac magnetic resonance imaging (MRI) and positron emission tomography (PET) scan demonstrated an infiltrative mass. Biopsy of a supraclavicular lymph node established a diagnosis of diffuse large B-cell lymphoma (DLBCL) with cardiac involvement. The patient was treated with corticosteroids and immunochemotherapy (DA-R-EPOCH), achieving complete remission on surveillance imaging. This case therefore contributes valuable evidence regarding the varied cardiovascular manifestations of lymphoma and reinforces the importance of maintaining a broad differential diagnosis in patients presenting with features of myocardial infarction with non-obstructive coronary arteries (MINOCA).
SN  - 2645-4904
ER  -