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Peer-reviewedCC BYNeurosurgical focus: Video

Multicompartmental hypothalamic craniopharyngioma resection via expanded endonasal endoscopic transplanum-transtuberculum approach.

  1. 1Department of Neurologic Surgery, University of Miami.
  2. 2Cranial Access, Neuroanatomy and ENT Surgical (CANES) Laboratory, University of Miami; and.
  3. 3Department of Otolaryngology-Head and Neck Surgery, University of Miami, Florida.

Abstract

Endoscopic endonasal surgery for hypothalamic craniopharyngiomas offers a tailored midline corridor maximizing resection while minimizing brain retraction. Tubero-infundibular lesions present severe technical challenges when engulfing the stalk. In this video, the authors demonstrate an expanded transplanum-transtuberculum approach for a multicompartmental adamantinomatous craniopharyngioma, incorporating detailed anatomical illustrations of the operative corridor. Driven by the case-specific complete tumor engulfment, infundibular stalk transection was the necessary maneuver to progress via tuber cinereum into the third ventricle to separate the lesion from the hypothalamic walls. The deliberate stalk sacrifice proved decisive for achieving safe gross-total resection in the presence of a clear hypothalamic-tumor surgical plane. The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID26112.

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BibTeX
@article{bonis2026multicompartmental,
  title = {{Multicompartmental hypothalamic craniopharyngioma resection via expanded endonasal endoscopic transplanum-transtuberculum approach.}},
  author = {Alessandro De Bonis and Gustavo Passos and Eva M Wu and Zoukaa Sargi and Carolina G Benjamin},
  journal = {Neurosurgical focus: Video},
  year = {2026},
  month = oct,
  doi = {10.3171/2026.7.focvid26112},
  url = {https://europepmc.org/article/MED/42948190},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Multicompartmental hypothalamic craniopharyngioma resection via expanded endonasal endoscopic transplanum-transtuberculum approach.
AU  - Alessandro De Bonis
AU  - Gustavo Passos
AU  - Eva M Wu
AU  - Zoukaa Sargi
AU  - Carolina G Benjamin
PY  - 2026
DA  - 2026/10/01
JO  - Neurosurgical focus: Video
DO  - 10.3171/2026.7.focvid26112
UR  - https://europepmc.org/article/MED/42948190
AB  - Endoscopic endonasal surgery for hypothalamic craniopharyngiomas offers a tailored midline corridor maximizing resection while minimizing brain retraction. Tubero-infundibular lesions present severe technical challenges when engulfing the stalk. In this video, the authors demonstrate an expanded transplanum-transtuberculum approach for a multicompartmental adamantinomatous craniopharyngioma, incorporating detailed anatomical illustrations of the operative corridor. Driven by the case-specific complete tumor engulfment, infundibular stalk transection was the necessary maneuver to progress via tuber cinereum into the third ventricle to separate the lesion from the hypothalamic walls. The deliberate stalk sacrifice proved decisive for achieving safe gross-total resection in the presence of a clear hypothalamic-tumor surgical plane. The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID26112.
SN  - 2643-5217
ER  -