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Peer-reviewedCC BY 4.0Neurosurgical Focus: Video

Management of a giant pediatric craniopharyngioma: staged endoscopic endonasal and cranial approaches

  1. 1Department of Neurosurgery, NYU Langone Health, New York
  2. 2Department of Oculoplastics, NYU Langone Health, New York; and
  3. 3Department of Otolaryngology, NYU Langone Health, New York, New York

Abstract

This report presents a complex case of an 8-year-old female with a giant 8-cm adamantinomatous craniopharyngioma. She had a mixed solid/cystic, multicompartmental tumor with brainstem compression, vascular encasement, obstructive hydrocephalus, and acute stroke on presentation. After neurological improvement with an external ventricular drain, she underwent an extended endonasal approach followed by a left supraorbital craniotomy to address the residual lateral tumor. We achieved a near gross-total resection with improvement in visual acuity, neurocognitive function, and hemiparesis. This case demonstrates that staged skull base approaches can lead to clinically significant and safe resections in the pediatric population.

The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID26136

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BibTeX
@article{save2026management,
  title = {{Management of a giant pediatric craniopharyngioma: staged endoscopic endonasal and cranial approaches}},
  author = {Akshay V. Save and Stella Chung and Carlos Pinheiro-Neto and Paul A. Gardner and Yosef M. Dastagirzada},
  journal = {Neurosurgical Focus: Video},
  year = {2026},
  month = oct,
  doi = {10.3171/2026.7.focvid26136},
  url = {https://doi.org/10.3171/2026.7.focvid26136},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Management of a giant pediatric craniopharyngioma: staged endoscopic endonasal and cranial approaches
AU  - Akshay V. Save
AU  - Stella Chung
AU  - Carlos Pinheiro-Neto
AU  - Paul A. Gardner
AU  - Yosef M. Dastagirzada
PY  - 2026
DA  - 2026/10/01
JO  - Neurosurgical Focus: Video
DO  - 10.3171/2026.7.focvid26136
UR  - https://doi.org/10.3171/2026.7.focvid26136
AB  - This report presents a complex case of an 8-year-old female with a giant 8-cm adamantinomatous craniopharyngioma. She had a mixed solid/cystic, multicompartmental tumor with brainstem compression, vascular encasement, obstructive hydrocephalus, and acute stroke on presentation. After neurological improvement with an external ventricular drain, she underwent an extended endonasal approach followed by a left supraorbital craniotomy to address the residual lateral tumor. We achieved a near gross-total resection with improvement in visual acuity, neurocognitive function, and hemiparesis. This case demonstrates that staged skull base approaches can lead to clinically significant and safe resections in the pediatric population.  The video can be found here: https://stream.cadmore.media/r10.3171/2026.7.FOCVID26136
SN  - 2643-5217
ER  -