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Peer-reviewedLicence not statedCell Research

Cryo-EM structures of Drosophila OR67d–Orco complexes reveal insect pheromone sensing mechanism

  • Jiangqin Wang1,2,3
  • Chuanyan Yang4
  • Shenghai Chang5
  • Dian Jiao2,3
  • Jiahao Lin6,7
  • Xiaotong Yang4
  • Weijie Cai4
  • Demin Ma2,4
  • Zhong Jie Ding8
  • Jia Huang9
  • Jianhua Huang9
  • Minrui Fan10
5 more authors
  • Meiqin Hu4
  • Yong Wang11,12
  • Haoxing Xu13,14
  • Nannan Su15
  • Jiangtao Guo16,17,18,19,20
20 affiliations
  1. 1Center for Membrane Receptors and Brain Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, China
  2. 2Department of Neurology of the Fourth Affiliated Hospital, and Department of Biophysics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
  3. 3Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China
  4. 4New Cornerstone Science Laboratory and Liangzhu Laboratory, the Second Affiliated Hospital and School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, China
  5. 5Center of Cryo-Electron Microscopy, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
  6. 6College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China
  7. 7The Provincial International Science and Technology Cooperation Base on Engineering Biology, International Campus of Zhejiang University, Haining, Zhejiang, China
  8. 8State Key Laboratory of Plant Environmental Resilience, College of Life Science, Zhejiang University, Hangzhou, Zhejiang, China
  9. 9Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang, China
  10. 10CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China
  11. 11College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China. [email protected]
  12. 12The Provincial International Science and Technology Cooperation Base on Engineering Biology, International Campus of Zhejiang University, Haining, Zhejiang, China. [email protected]
  13. 13Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA. [email protected]
  14. 14New Cornerstone Science Laboratory and Liangzhu Laboratory, the Second Affiliated Hospital and School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, China. [email protected]
  15. 15Center for Membrane Receptors and Brain Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, China. [email protected]
  16. 16Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China. [email protected]
  17. 17Department of Neurology of the Fourth Affiliated Hospital, and Department of Biophysics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. [email protected]
  18. 18NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Science and Brain-machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang, China. [email protected]
  19. 19Nanhu Brain-computer Interface Institute, Hangzhou, Zhejiang, China. [email protected]
  20. 20State Key Laboratory of Plant Environmental Resilience, College of Life Science, Zhejiang University, Hangzhou, Zhejiang, China. [email protected]
Open at sourceDOICite

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Cite

BibTeXRIS
BibTeX
@article{wang2026cryoem,
  title = {{Cryo-EM structures of Drosophila OR67d–Orco complexes reveal insect pheromone sensing mechanism}},
  author = {Jiangqin Wang and Chuanyan Yang and Shenghai Chang and Dian Jiao and Jiahao Lin and Xiaotong Yang and Weijie Cai and Demin Ma and Zhong Jie Ding and Jia Huang and Jianhua Huang and Minrui Fan and Meiqin Hu and Yong Wang and Haoxing Xu and Nannan Su and Jiangtao Guo},
  journal = {Cell Research},
  year = {2026},
  month = jun,
  doi = {10.1038/s41422-026-01264-2},
  url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC13424369/},
}
RIS
TY  - JOUR
TI  - Cryo-EM structures of Drosophila OR67d–Orco complexes reveal insect pheromone sensing mechanism
AU  - Jiangqin Wang
AU  - Chuanyan Yang
AU  - Shenghai Chang
AU  - Dian Jiao
AU  - Jiahao Lin
AU  - Xiaotong Yang
AU  - Weijie Cai
AU  - Demin Ma
AU  - Zhong Jie Ding
AU  - Jia Huang
AU  - Jianhua Huang
AU  - Minrui Fan
AU  - Meiqin Hu
AU  - Yong Wang
AU  - Haoxing Xu
AU  - Nannan Su
AU  - Jiangtao Guo
PY  - 2026
DA  - 2026/06/10
JO  - Cell Research
DO  - 10.1038/s41422-026-01264-2
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC13424369/
SN  - 1001-0602
SN  - 1748-7838
ER  -