Pediatric venous thromboembolism: an illustrated review
- 1Department of Pediatrics, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA; Louisiana Center for Bleeding & Clotting Disorders, New Orleans, Louisiana, USA
- 2Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, Louisiana, USA; Louisiana Center for Bleeding & Clotting Disorders, New Orleans, Louisiana, USA
Abstract
Venous thromboembolism (VTE) in children has historically been considered uncommon; however, it is increasingly recognized in hospitalized pediatric populations, and its incidence has risen over the past few decades. This can be attributed to several factors, including greater awareness of the condition, improved survival rates for children with chronic and complex medical conditions, increased use of supportive care (such as central venous catheters), and advancements in diagnostic imaging. Acquired conditions, such as infections, malignancies, cardiovascular diseases, and inflammatory bowel disease, are recognized as risk factors for VTE. Among these, the presence of a central venous catheter remains the most significant and common risk factor for pediatric VTE. In this review, we present and illustrate the pathophysiology and current treatment options for VTE in the pediatric population.
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BibTeX
@article{espanol2026pediatric,
title = {{Pediatric venous thromboembolism: an illustrated review}},
author = {Maria G. Espanol and Maissaa Janbain},
journal = {Research and Practice in Thrombosis and Haemostasis},
year = {2026},
month = aug,
doi = {10.1016/j.rpth.2026.106892},
url = {https://doi.org/10.1016/j.rpth.2026.106892},
note = {CC BY},
}
RIS
TY - JOUR
TI - Pediatric venous thromboembolism: an illustrated review
AU - Maria G. Espanol
AU - Maissaa Janbain
PY - 2026
DA - 2026/08/01
JO - Research and Practice in Thrombosis and Haemostasis
DO - 10.1016/j.rpth.2026.106892
UR - https://doi.org/10.1016/j.rpth.2026.106892
AB - Venous thromboembolism (VTE) in children has historically been considered uncommon; however, it is increasingly recognized in hospitalized pediatric populations, and its incidence has risen over the past few decades. This can be attributed to several factors, including greater awareness of the condition, improved survival rates for children with chronic and complex medical conditions, increased use of supportive care (such as central venous catheters), and advancements in diagnostic imaging. Acquired conditions, such as infections, malignancies, cardiovascular diseases, and inflammatory bowel disease, are recognized as risk factors for VTE. Among these, the presence of a central venous catheter remains the most significant and common risk factor for pediatric VTE. In this review, we present and illustrate the pathophysiology and current treatment options for VTE in the pediatric population.
SN - 2475-0379
ER -