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PreprintCC BY 4.0HAL

Toward High-Resolution Detection of Target Fragmentation: TEA-Sensitized NIT for Proton Therapy Applications

87 more authors

60 listed; 99 in total.

Abstract

Nano Imaging Trackers (NIT) are fine-grained nuclear emulsions capable of tracking charged particles with sub-micrometric spatial resolution. The DAMON (Direct Measurement of Target Fragmentation) experiment recently employed NIT to detect target-fragmentation events relevant to proton therapy in direct kinematics. These measurements showed that the small crystal size, while providing high spatial resolution, limits the reconstruction efficiency for primary proton tracks and high-energy secondary protons. This work reports an enhancement of NIT sensitivity achieved through alternative chemical sensitization methods, namely gold-plus-sulfur (Au-S) and triethanolamine (TEA), together with the use of the GR-1 developer. The detector response was evaluated with gamma-ray, carbon-ion and proton exposures, including clinically relevant proton energies.

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BibTeX
@misc{boccia2026toward,
  title = {{Toward High-Resolution Detection of Target Fragmentation: TEA-Sensitized NIT for Proton Therapy Applications}},
  author = {V Boccia and T Asada and A Alexandrov and G Ambrosi and S Argirò and M Barbanera and N Bartosik and G Battistoni and A Bigot and M.G Bisogni and G Butella and F Cavanna and P Cerello and E Ciarrocchi and N d'Ambrosio and G de Lellis and A Di Crescenzo and B Di Ruzza and M Dondi and M Donetti and Y Dong and M Durante and R Faccini and V Ferrero and C Finck and E Fiorina and M Francesconi and M Franchini and G Franciosini and L Galli and A Luliano and K Kanxheri and B Kharpuse and M Kimura and S Kodaira and A.C Kraan and A Lauria and E Lopez Torres and T Maggipinto and M Magi and A Manna and M Marafini and S Masci and M Massa and C Massimi and I Mattei and S Mazzolani and A Mengarelli and A Mereghetti and R Mirabelli and A Moggi and M.C Montesi and M.C Morone and M Morrocchi and S Muraro and T Naka and N Pastrone and V Patera and F Pennazio and C Pisanti},
  howpublished = {HAL},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.02337},
  eprint = {2609.02337},
  archivePrefix = {arXiv},
  url = {https://hal.science/hal-05758461v1},
  note = {CC BY 4.0},
}
RIS
TY  - UNPB
TI  - Toward High-Resolution Detection of Target Fragmentation: TEA-Sensitized NIT for Proton Therapy Applications
AU  - V Boccia
AU  - T Asada
AU  - A Alexandrov
AU  - G Ambrosi
AU  - S Argirò
AU  - M Barbanera
AU  - N Bartosik
AU  - G Battistoni
AU  - A Bigot
AU  - M.G Bisogni
AU  - G Butella
AU  - F Cavanna
AU  - P Cerello
AU  - E Ciarrocchi
AU  - N d'Ambrosio
AU  - G de Lellis
AU  - A Di Crescenzo
AU  - B Di Ruzza
AU  - M Dondi
AU  - M Donetti
AU  - Y Dong
AU  - M Durante
AU  - R Faccini
AU  - V Ferrero
AU  - C Finck
AU  - E Fiorina
AU  - M Francesconi
AU  - M Franchini
AU  - G Franciosini
AU  - L Galli
AU  - A Luliano
AU  - K Kanxheri
AU  - B Kharpuse
AU  - M Kimura
AU  - S Kodaira
AU  - A.C Kraan
AU  - A Lauria
AU  - E Lopez Torres
AU  - T Maggipinto
AU  - M Magi
AU  - A Manna
AU  - M Marafini
AU  - S Masci
AU  - M Massa
AU  - C Massimi
AU  - I Mattei
AU  - S Mazzolani
AU  - A Mengarelli
AU  - A Mereghetti
AU  - R Mirabelli
AU  - A Moggi
AU  - M.C Montesi
AU  - M.C Morone
AU  - M Morrocchi
AU  - S Muraro
AU  - T Naka
AU  - N Pastrone
AU  - V Patera
AU  - F Pennazio
AU  - C Pisanti
PY  - 2026
DA  - 2026/09/03
PB  - HAL
DO  - 10.48550/arxiv.2609.02337
UR  - https://hal.science/hal-05758461v1
AB  - Nano Imaging Trackers (NIT) are fine-grained nuclear emulsions capable of tracking charged particles with sub-micrometric spatial resolution. The DAMON (Direct Measurement of Target Fragmentation) experiment recently employed NIT to detect target-fragmentation events relevant to proton therapy in direct kinematics. These measurements showed that the small crystal size, while providing high spatial resolution, limits the reconstruction efficiency for primary proton tracks and high-energy secondary protons. This work reports an enhancement of NIT sensitivity achieved through alternative chemical sensitization methods, namely gold-plus-sulfur (Au-S) and triethanolamine (TEA), together with the use of the GR-1 developer. The detector response was evaluated with gamma-ray, carbon-ion and proton exposures, including clinically relevant proton energies.
ER  -