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Peer-reviewedCC BY-NC-ND 4.0Stem Cell Reports

The transformative impact of stem cell core facilities in biomedical research

  • Barbara Corneo
  • Giovanni Faga
  • Inês Figueira
  • Jacopo Zasso
  • Wenli Yang
  • Katrin Neuman
  • Pia Johansson
  • Lyn Healy
  • Laurence Daheron
  • Melanie Generali
  • Ole Pless
  • Ras Trokovic
3 more authors
  • Laurent David
  • Mehrnaz Gazhvini
  • Laura Batlle-Morera
Open at sourcePDFDOICite

Abstract

Over the past three decades, advances in human pluripotent stem cell (hPSC) technologies, including induced pluripotent stem cells, gene editing, and 2D/3D models, have transformed biomedical research. These powerful tools have revolutionized disease modeling, drug discovery, and the development of advanced therapy medicinal products (ATMPs), while driving the establishment of stem cell core facilities. By providing specialized expertise, standardized workflows, and access to advanced technologies, these facilities support both fundamental and translational research, promote rigor and reproducibility, and foster collaboration. This manuscript highlights their role as hubs of excellence and discusses current challenges and future opportunities for the global stem cell community.

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Cite

BibTeXRIS
BibTeX
@article{corneo2026transformative,
  title = {{The transformative impact of stem cell core facilities in biomedical research}},
  author = {Barbara Corneo and Giovanni Faga and Inês Figueira and Jacopo Zasso and Wenli Yang and Katrin Neuman and Pia Johansson and Lyn Healy and Laurence Daheron and Melanie Generali and Ole Pless and Ras Trokovic and Laurent David and Mehrnaz Gazhvini and Laura Batlle-Morera},
  journal = {Stem Cell Reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.stemcr.2026.103047},
  url = {https://inserm.hal.science/inserm-05778787v1},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - The transformative impact of stem cell core facilities in biomedical research
AU  - Barbara Corneo
AU  - Giovanni Faga
AU  - Inês Figueira
AU  - Jacopo Zasso
AU  - Wenli Yang
AU  - Katrin Neuman
AU  - Pia Johansson
AU  - Lyn Healy
AU  - Laurence Daheron
AU  - Melanie Generali
AU  - Ole Pless
AU  - Ras Trokovic
AU  - Laurent David
AU  - Mehrnaz Gazhvini
AU  - Laura Batlle-Morera
PY  - 2026
DA  - 2026/10/05
JO  - Stem Cell Reports
DO  - 10.1016/j.stemcr.2026.103047
UR  - https://inserm.hal.science/inserm-05778787v1
AB  - Over the past three decades, advances in human pluripotent stem cell (hPSC) technologies, including induced pluripotent stem cells, gene editing, and 2D/3D models, have transformed biomedical research. These powerful tools have revolutionized disease modeling, drug discovery, and the development of advanced therapy medicinal products (ATMPs), while driving the establishment of stem cell core facilities. By providing specialized expertise, standardized workflows, and access to advanced technologies, these facilities support both fundamental and translational research, promote rigor and reproducibility, and foster collaboration. This manuscript highlights their role as hubs of excellence and discusses current challenges and future opportunities for the global stem cell community.
SN  - 2213-6711
ER  -